Introduction and Objective: ADA Standards of Care recommend screening for and addressing elevated DD, yet implementation is challenging. We built a validated, 8-item screener (T1-DDAS) into EPIC in the online e-CheckIn process for adults with T1D. A positive screen for DD (>= 2.0) generates a Best Practice Advisory (BPA) notification during the clinical encounter with […]
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1959-LB: Successful Nationwide Expansion of the Local Stuttgart Ketoacidosis Prevention Campaign in Germany—Which Parameters Are Important for Awareness Campaigns?
Introduction and Objective: Following the successful implementation of the Stuttgart Diabetic Ketoacidosis (DKA) Prevention Campaign at local level, we have extended this proven concept to the Federal State of Baden-Wuerttemberg (BW) in Germany.Methods: All public health departments (PHD) in BW were invited over 3 years to hand out flyers and posters about the typical symptoms […]
Read More601-P: Diabetes Self-Efficacy—Longitudinal Relationships with Diabetes Overall Self-Management, Medication Adherence, Diabetes Distress, and Glycemic Control in Adults with Type 2 Diabetes
Introduction and Objective: Self-efficacy and diabetes distress are inextricably linked to coping with diabetes. The role of diabetes distress in the relationship between diabetes self-efficacy and glycemic control in T2DM over time is understudied. The objective of this study was to evaluate the longitudinal associations of self-efficacy with overall diabetes self-management, medication adherence, diabetes distress, […]
Read More886-P: A Novel UCN2 Analog HM17321 with HM15275 Improves Body Composition in Mouse Model of Obesity
Introduction and Objective: Incretin drugs have demonstrated remarkable efficacy in body weight reduction and improving metabolic parameters. However, there may be challenges associated with lean mass loss and long-term health benefits. Urocortin-2 (UCN2) is a corticotropin-releasing factor receptor 2 (CRFR2) agonist and has been known to regulate whole body glucose metabolism, insulin sensitivity and skeletal […]
Read More524-P: Culturally Competent Diabetes Management—Addressing Access for Limited English Proficient Patients
Introduction and Objective: Diabetes affects all cultures, yet inequities persist, especially among minority groups who often receive lower-quality care. Language barriers lead to inadequate blood sugar control and reduced engagement in Diabetes Self-Management Education (DSME). This report evaluates the effectiveness of a DSME team in integrating culturally competent translated care into primary care, enhancing services […]
Read More883-P: Metabolic Endotoxemia and Gut Microbiota Associated with Therapeutic Responses to Metformin in Type 2 Diabetes
Introduction and Objective: Metformin, the first-line treatment for type 2 diabetes, exerts antidiabetic effects partly through gut microbiota modulation. However, it can also increase Escherichia species capable of inducing endotoxemia via lipopolysaccharide (LPS). This study investigated metabolic endotoxemia, represented by LPS-binding protein (LBP) and its antagonist bactericidal/permeability-increasing protein (BPI), in relation to therapeutic responses to […]
Read More523-P: Seeking Methods to Engage Emerging Adults (EAs) with Type 1 Diabetes (T1D) in Diabetes Self-Management Education and Support (DSMES)—A Human-Centered Design Approach
Introduction and Objective: DSMES is considered a cornerstone of diabetes care. EAs with T1D are reported to have alarmingly low DSMES participation rates yet doing most of their self-care. In its present form, DSMES has been cited for not meeting EAs’ needs. Our objective was to discover factors affecting DSMES engagement and use a collaborative […]
Read More1678-P: Weight-Independent GLP-1RA Effects on Adipose Tissue PGC1-α and TERT in Insulin-Resistant Humans
Introduction and Objective: Induced adipocyte browning, in limited subcutaneous adipose tissue (SAT) human depots via cold activation or weight loss, confers anti-diabetic/obesity function via thermogenesis. Peroxisome proliferator-activated receptor-γ coactivator (PGC1-α) regulates mitochondrial biogenesis in adipose tissue (AT), and may activate telomerase reverse transcriptase (TERT), which regulates cellular aging. AT browning exists in GLP-1RA-treated patients with […]
Read More522-P: Utilization of Personal Continuous Glucose Monitoring (CGM) Systems in the Inpatient Setting
Introduction and Objective: This pilot study sought to compare glucose outcomes and provider insulin dosing confidence in individuals using personal CGM while in the hospital compared to those receiving point of care blood glucose (POC BG) monitoring only.Methods: Hospitalized individuals followed by the diabetes service and expected to be discharged on insulin were included. Diabetes […]
Read More652-P: Effectiveness of a Digital Lifestyle Intervention for Glycemic Control in People with Type 2 Diabetes
Introduction and Objective: This study aims to evaluate the effectiveness of a digital lifestyle-based interventional program, developed by us, [D-LITE (Diabetes- Lifestyle Intervention for Therapeutic Enhancement)], on metabolic control in individuals with diabetes.Methods: An online diabetes management program utilizing a WhatsApp-based model facilitated continuous and collaborative care among patient, a dietitian, and physicians. The program […]
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