Sugar is Not Your Friend

Introduction and Objective: Teplizumab (TPZ), an anti-CD3 monoclonal antibody, is approved in the US to delay stage 3 T1D onset in individuals aged ≥8 years (y) with stage 2 T1D. We present screening and real-world treatment (Tx) patterns from individuals in the US who received TPZ according to their age group.Methods: TEPLI-REAL (NCT06892002) was a […]

Introduction and Objective: Insulin-like growth factor-1 receptor (IGF-1R) inhibitor has been developed as an effective therapy for thyroid eye disease (TED). However, treatment-associated hyperglycemia remains a clinical concern. We aimed to examine whether early glycemic deterioration during IGF-1R inhibitor therapy is associated with subsequent glycemic trajectories and to develop and validate a risk prediction model.Methods: […]

Introduction and Objective: The Diabetes Prevention Program’s (DPP) standardized goal of ≥150 mins of physical activity (PA)/week leads to long-term health benefits. We examined the association between virtual DPP PA goal attainment and three distinct program engagement components: session completion, self-monitoring, and social interactions.Methods: We included women Veterans participating in virtual DPP across 11 VA […]