Introduction and Objective: Automated insulin delivery (AID) systems adjust insulin delivery based on real-time glucose readings, offering potential advantages over open-loop insulin delivery (OLID). Ramadan fasting presents unique challenge for individuals with type 1 diabetes (T1D) due to significant fluctuations in glucose levels. This study aimed to identify the predictor factors associated with achieving better […]
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1429-P: Planetary Health Diet—Associations with Cardiovascular Disease and Type 2 Diabetes Risks, and Long-Term Weight Change in Women with a History of Gestational Diabetes
Introduction and Objective: The Planetary Health Diet (PHD), introduced in 2019 by the EAT-Lancet Commission, promotes chronic disease prevention and environmental sustainability. However, evidence on PHD adherence and its association with type 2 diabetes (T2D), cardiovascular disease (CVD), and weight gain is scarce, especially among women with a history of gestational diabetes mellitus (GDM).Methods: We […]
Read More926-P: Automated Insulin Delivery vs. Open-Loop Insulin Delivery during Ramadan in Patients with Type 1 Diabetes in Saudi Arabia—The Hybrid-Ram Randomized Controlled Trial
Introduction and Objective: Automated insulin delivery (AID) systems, adjusting insulin based on real-time glucose readings, may offer advantages over open-loop insulin delivery (OLID), especially during Ramadan fasting, which poses challenges for individuals with type 1 diabetes (T1D).Methods: This dual-center, open-label, randomized controlled trial compared AID systems (Medtronic MiniMed 780G [M780] and Tandem T-slim Control IQ […]
Read More1659-P: Oxytocin Is Robustly Expressed throughout the Small Intestine in Individuals with and without Type 2 Diabetes and Serum Neurophysin I Levels Are Reduced after Roux-en-y Gastric Bypass
Introduction and Objective: Oxytocin has been proposed to have anorexigenic effects and the gene is among the most upregulated in the small intestine after Roux-en-Y gastric bypass (RYGB) surgery. We evaluated oxytocin and oxytocin receptor gene expression along the intestinal tract in individuals with and without type 2 diabetes, and assessed circulating concentrations of the […]
Read More925-P: Real-World Outcomes of the Integration of Omnipod 5 Insulin Pump and Freestyle Libre 2 plus Continuous Glucose Monitoring in Adults with Type 1 Diabetes
Introduction and Objective: Hybrid closed-loop (HCL) therapy has revolutionized the care for people living with type 1 diabetes (pwT1D). The integration of different technology devices evolves rapidly providing individuals with more options and flexibility. We aimed to assess real-world outcomes of the new HCL system integrating the tubeless Omnipod 5 insulin pump with FreeStyle Libre […]
Read More1258-P: Fasting Triglycerides Are Unaffected by Weekday Variation in Obese Pregnancy But Steadily Increase over Gestation—Implications for Prevention of Macrosomia
Introduction and Objective: The role of maternal lipids, especially triglycerides (TG), in contributing to excess fetal fat accretion in pregnancies affected by obesity or diabetes is of increasing interest, given supportive data in obesity. Outside of pregnancy, fasting TG (FTG) are reported as higher on Mondays, after the weekend. No such data exists in pregnancy. […]
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Heart Attack Deaths Decline in U.S., but Other Heart Issues Are Increa
Share on PinterestHeart disease overall has decreased by 66% since 1970, but it remains the leading cause of death among Americans. Tashdique Mehtaj Ahmed/Getty Images Heart attacks have become more survivable in the past 50 years, and are no longer the leading cause of heart disease-related deaths, a new study reports. As heart attack deaths […]
Read More924-P: Predictors of Diabetes-Related Distress following Closed-Loop Initiation in Adults with Type 1 Diabetes in the UK—Insights from the Association of British Clinical Diabetologists
Introduction and Objective: The National Health Service (NHS) England hybrid closed-loop (HCL) pilot provided access to HCL for adults with type 1 diabetes (T1D), managed with an insulin pump and intermittently scanned continuous glucose monitoring, with a HbA1c ≥8.5%. We assessed the factors associated with improved diabetes-related distress (DRD) at follow up.Methods: Anonymized baseline and […]
Read More332-OR: Social Isolation and Loneliness and Stroke Risk in Men and Women with Diabetes
Introduction and Objective: We evaluated the association between social isolation, loneliness, and stroke risk in individuals with diabetes (DM) (vs. euglycemia) and assessed sex differences in the association.Methods: We included participants with DM (N=40,684) (defined by self-reported DM diagnosis, DM medication, HbA1c>6.5%, ICD codes) and sex-, race-, age-, and center-matched euglycemic individuals (1:1) from the […]
Read More923-P: Fasting Experience, Glycemic Control, and Fear of Hypoglycemia in People with Type 1 Diabetes Using Open-Source vs. Commercial Automated Insulin Delivery during Ramadan—A Multicenter Study from Saudi Arabia
Introduction and Objective: Open-source automated insulin delivery (OS-AID) has been shown to improve glycemic control in people with type 1 diabetes (PWT1D). We compare the effectiveness, safety, and fear of hypoglycemia (FOH) between OS-AID and commercial (C-AID) systems during Ramadan fasting.Methods: We recruited 114 PWT1D fasting during Ramadan 2024 using an AID system [OS-AID (n=7) […]
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