Category: Diabetes

Introduction and Objective: Health inequities continue to drive disparities in diabetes outcomes across the United States. To help identify barriers to facilitators of health equity improvement, the T1D Exchange QI Collaborative conducted an assessment of member centers.Methods: The annual T1DX-QI survey was administered via Qualtrics from August to October 2025 to collect data from 2023. […]

Introduction and Objective: Gastrointestinal tolerability is a key consideration for weight loss therapies targeting appetite-regulating pathways. Conditioned taste avoidance (CTA) in rodents is a widely used preclinical model to evaluate the potential of compounds to produce nausea and gastrointestinal discomfort. We compared food intake inhibition and CTA responses induced by a small molecule amylin receptor […]

Introduction and Objective: There are more than 101 million individuals living with diabetes in India.Meeting treatment goals for HbA1c, Blood pressure and Cholesterol(ABC) can help prevent diabetes complications.We assessed diabetes awareness, management gaps and attainment of ABC goals among rural South Indian with self-reported diabetes.Methods: The Telemedicine pRoject for screENing Diabetes and its complications in […]

Introduction and Objective: GLP-1 receptor activation and amylin receptor activation are two complementary mechanisms of action for obesity treatments. Combination therapy of long-acting peptides semaglutide and cagrilintide have demonstrated enhanced efficacy over single agents for obesity treatment in clinical trials. Small molecules offer potential advantages over peptides, including scalability, room temperature shipping and storage, and […]

Introduction and Objective: To explore whether short-term intensive glucose control can minimize the escalation of treatment in poorly controlled type 2 diabetes.Methods: Patients with poorly controlled type 2 diabetes despite receiving two or more hypoglycemic agents were randomly assigned to three intensive glucose control groups, with a 36-week core period followed by a 24-week extension. […]

Introduction and Objective: Patients with T2D can be clustered into distinct etiologic subgroups, but it is not clear if the same is true for those with prediabetes (preDM). As metabolites mark the onset of T2D prior to clinical thresholds, we clustered individuals with preDM by preDM-related metabolites and examined subgroups for long-term T2D risk.Methods: Data […]

Introduction and Objective: T1D population health requires synthesizing multiple data points. GRI summarizes severity-weighted hypo/hyperglycemia into zone categories. We assessed whether GRI can be used to characterize a pediatric cohort in relation to CGM targets.Methods: We analyzed up to 24 months of CGM data in 225 children with T1D and calculated GRI in consecutive 14-day […]

Introduction and Objective: All-cause mortality has been on the decline among people with type 1 diabetes (T1D). Despite this trend, excess mortality remains high among people with T1D compared to those without T1D. We examined the all-cause and cause-specific mortality in a contemporary T1D cohort and explored factors that influenced mortality.Methods: Participants in the Coronary […]

Introduction and Objective: Annual eye examinations for diabetes (EEDs) are essential for early detection of diabetic retinopathy, yet adherence remains suboptimal, particularly in rural communities where access to eye care is limited. Autonomous AI systems offer a scalable approach to expand patient access at the point of care. We evaluated the real-world impact of LumineticsCore™, […]

Introduction and Objective: Rapid postprandial glucose rises during pregnancy may adversely affect offspring health, while practical dietary advice for gestational diabetes remains limited. In type 2 diabetes, premeal whey protein (WP) reduces postprandial blood glucose. We investigated whether preprandial WP attenuates glucose excursions after carbohydrate intake in pregnant women and explored underlying mechanisms.Methods: In this […]