Introduction and Objective: This study examines the impact of Sodium-glucose cotransporter 2 inhibitors (SGLT2is) and metformin on severe Lower extremity arterial disease (LEAD) progression in elderly patients with type 2 diabetes (T2D). Using propensity score matching, a three-year analysis compares their distinct effects on risk using a real-world claims database.Methods: This retrospective cohort study analyzed […]
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2124-LB: Characteristics of People with Monogenic Diabetes in the Rare and Atypical Diabetes Network (RADIANT) Cohort
Introduction and Objective: Monogenic diabetes (MD) accounts for 0.4% of all cases of diabetes and 1-5% of youth-onset diabetes. Diagnosis allows for improved care with targeted therapy and identification of affected relatives. However, several barriers currently prevent patients from receiving diagnoses. We aimed to elucidate the proportion of individuals with undiagnosed MD within the Rare […]
Read More580-P: Engagement across DiabetesWise—A Platform for Support around Diabetes Technology and Exercise
Introduction and Objective: To gain feedback from users and assess engagement with the DiabetesWISER (DWer) community forum and DiabetesWise (DW) website – a neutral and unbiased platform for diabetes technology and exercise resources.Methods: User testing was conducted to understand needs and utilization patterns of people with diabetes and healthcare providers (HCPs) using these platforms.Results: During […]
Read More557-P: Diabetes Conditional Cash Transfer (DM-CCT) Intervention to Improve Glycemic Control—A Pilot Randomized Controlled Trial
Introduction and Objective: A pilot randomized controlled trial among inner-city African Americans with poorly controlled type 2 diabetes (HbA1c >=8%) tested the feasibility and preliminary efficacy of conditional and unconditional cash transfers.Methods: 100 participants were randomized to receive: 1) unconditional cash transfers (UCT) of $500 per month for 6 months and mailed diabetes education every […]
Read More57-PUB: CytoProfile—Advancing Cytokine Profiling Analysis with R
Introduction and Objective: Cytokine profiling is crucial in understanding immune responses and disease mechanisms, yet existing analytical tools often fall short in addressing the unique complexities of cytokine data. This study introduces CytoProfile, an R-based software tailored for comprehensive cytokine analysis. The objective was to evaluate its integration of advanced statistical and machine learning methods […]
Read More2024-LB: Dexcom G7 rtCGM Shows Improved Accuracy and Glycemia Compared with Dexcom G6 in Critically Ill Inpatient Adults
Introduction and Objective: This study compared accuracy and glycemic control using Dexcom G6 and G7 real-time continuous glucose monitors (rtCGM) integrated into an insulin infusion computer calculator (IICC) workflow for critically ill adult inpatients.Methods: A retrospective analysis evaluated 13 ICU patients using Dexcom G6 and 35 using G7, integrated into an institution-developed IICC workflow using […]
Read More57-OR: Family Intervention Effects on Parenting and Adolescent Glycemic and Psychosocial Outcomes
Introduction and Objective: To evaluate effects of a family program on adolescents with type 1 diabetes and their parents.Methods: Parent-adolescent dyads (n=157) were randomly assigned to the intervention condition or a waitlisted control. The intervention included 6 weekly 30-minute sessions for dyads to meet with an interventionist to learn communication and problem-solving skills related to […]
Read More1049-P: Health Care Costs and Utilization among Patients Eligible for Continuous Glucose Monitors—A Comparison of Users and Nonusers
Introduction and Objective: Continuous glucose monitors (CGMs) are recommended for individuals with diabetes using rapid- or short-acting insulin, but many eligible individuals do not use them. This study compared healthcare costs and utilization between CGM users and non-users.Methods: Claims data from the Mariner Commercial Claims Database (January 1, 2010-April 30, 2022) were analyzed. Adults (≥18 […]
Read More578-P: Resistance Training Prevents the Progression of Diabetec Nephropathy in Patients with 2 Diabetes
Introduction and Objective: Diabetic nephropathy is one of the most important complications of diabetes mellitus. In recent years, exercise has been reported to be potentially effective in preventing nephropathy. However, the relationship with resistance training(RT) is not clear. In this study, we researched the effect of resistance RT on the progression of nephropathy in patients […]
Read More751-P: The Risk of Acute Pancreatitis and Biliary Events after Initiation of GLP-1RA, SGLT2i, or DPP-4i in Patients with T2D
Introduction and Objective: Patients with type 2 diabetes (T2D) are at increased risk of acute pancreatitis (AP) and biliary events. Existing evidence is mixed regarding the association between second-line diabetes medications and AP and biliary events.Methods: Using Medicare and 2 U.S. private health plans (2014-2021), we identified three pairwise cohorts of propensity score (PS) fine […]
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