Share on PinterestRumer Willis is sharing how hormone tracking helped her better understand her cycle, and why she’s encouraging other women to better understand their reproductive health. Photo by Victoria Wall Harris Rumer Willis says hormone tracking helped her better understand her cycle. Experts say at-home hormone tests may help confirm ovulation and guide fertility […]
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AHA Highlights Benefits, Safety Limits for Heart Health
Share on PinterestThe American Heart Association (AHA) states that up to 5 cups of black coffee a day is safe for most people. Image Credit: Filmstax/Getty The American Heart Association (AHA) published a statement confirming how much caffeinated coffee is safe to drink each day. Adding flavorings like sugar, cream, and syrups to coffee can […]
Read MoreMorning Elevation in Insulin Enhances Afternoon Hepatic Glucose Disposal in Dogs by Increasing Both Insulin Signaling and Glucose Action
The second-meal phenomenon refers to the improved glycemic response to a subsequent identical meal. We previously showed that morning hyperinsulinemia is a key mediator, priming the liver for enhanced net hepatic glucose uptake (NHGU) and glycogen storage during an afternoon hyperinsulinemic-hyperglycemic clamp. Postprandial NHGU is regulated by three primary mechanisms: insulin action, initiated by hyperinsulinemia; […]
Read MoreFDA May Ease Restrictions Despite Concerns From Experts
Share on PinterestPhoto taken on Aug. 23, 2021 shows the U.S. Food and Drug Administration in Silver Spring, Maryland, the United States. (Photo by Ting Shen/Xinhua via Getty Images) An FDA advisory panel is expected to vote on whether to allow seven types of peptides to be sold as compounded medications. Proponents describe wellness peptides […]
Read MoreRBP4 Aggravates Diabetic Retinopathy by Inducing Microglial Activation and Endothelial Inflammation
Diabetic retinopathy (DR) is recognized as an inflammatory neurovascular complication, with neuronal deficits preceding vascular symptoms. This study identified elevated serum retinol-binding protein 4 (RBP4) as a risk factor for DR, because it induces retinal neuronal injuries and exacerbates vascular defects. Vitreous RBP4 levels were significantly elevated in patients with DR compared with those with […]
Read MoreEating an Avocado a Day May Lower Your Risk
Share on PinterestResearch shows that eating an avocado a day may help reduce heart disease risk in people with obesity. Image Credit: Thai Liang Lim/Getty A recent study has found that eating an avocado a day may help lower the risk of heart disease in people with obesity. The researchers found that this was associated […]
Read Moreα/β-Hydrolase Domain Containing 5 Supports Glucose-Stimulated Lipolysis and Insulin Secretion in Pancreatic β-Cells
Adipose triglyceride (TG) lipase (ATGL) is the rate-limiting enzyme of TG catabolism at the surface of lipid droplets (LDs). In pancreatic β-cells, lipolysis by ATGL increases with glucose and produces metabolites that support glucose-stimulated insulin secretion (GSIS). Upregulation of lipolysis by glucose is blunted in human islets affected by type 2 diabetes. However, how glucose […]
Read MoreErratum. Unilateral Primary Aldosteronism Lacking KCNJ5 Somatic Mutations Is Associated With an Elevated Risk of New-Onset Diabetes. Diabetes 2025;74:850–859
In the article cited above, the first affiliation for author Chieh-Kai Chan was incomplete as published. The complete affiliation is Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu City, Taiwan. Source link
Read MoreNanofibrous Bioabsorbable Functionalized Scaffolds Augment Subcutaneous Islet Engraftment and Function in Mice
The subcutaneous (SQ) space is a promising site for islet transplantation to treat type 1 diabetes. We hypothesize that nanofibrous bioabsorbable functionalized scaffolds (BAFS) implanted in the SQ space will create a highly vascularized niche that will support islet engraftment. Electrospun poly(lactic-co-glycolic acid) (PLGA) and gelatin (G) (PLGA + G) scaffolds functionalized with vascular endothelial growth factor […]
Read MoreMASLD as Complication of Diabetes
Worldwide metabolic dysfunction–associated steatotic liver disease (MASLD) is the leading cause of chronic liver disease. Despite high global prevalence, MASLD is not yet recognized as a noncommunicable disease, although all of the criteria are fulfilled for such a classification. MASLD is strongly associated with type 2 diabetes, cardiovascular disease, chronic kidney disease, and certain extrahepatic […]
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