Month: June 2026

Introduction and Objective: Lifestyle-related circadian disruption, including night-shift work, increases susceptibility to obesity and type 2 diabetes. However, the long-term effects of maternal circadian misalignment during pregnancy on metabolic health of adult offspring remain unclear. We investigated whether gestational circadian disruption, modeled using a short-day (SD) light cycle, programs offspring for metabolic dysfunction.Methods: Pregnant C57BL/6J […]

Introduction and Objective: Reversion to normoglycemia is increasingly recognized as a key goal in pre-diabetes management. Weight loss is a vital strategy to facilitate prediabetes reversion. This study assessed the association of weight change patterns with prediabetes reversion.Methods: Data were from the China Health and Retirement Longitudinal Study Waves 1-3 (2011, 2013, and 2015). Participants […]

Introduction and Objective: Diabetes-related stigma in healthcare professionals has been shown to negatively affect the mental health, disease self-management, and clinical outcomes (e.g., HbA1c) of people with diabetes. However, little is known about how this stigma varies among medical students. Understanding these differences is crucial for identifying future healthcare professionals most vulnerable to stigmatized attitudes […]

Introduction and Objective: Hypokalemia is associated with adverse cardiovascular outcomes in heart failure (HF) and may impair insulin release and action. However, whether hypokalemia promotes incident diabetes in HF is uncertain.Methods: In this FINEARTS-HF analysis, we evaluated the association between time-updated serum potassium levels and new-onset diabetes, defined as ≥2 HbA1c measurements ≥6.5% or initiation […]

Introduction and Objective: The rate of hypertensive disorders of pregnancy (HDP) is rising. HDP has been linked to pre-existing cardiometabolic (CM) risk factors, including insulin resistance (IR), BMI, blood lipids, and lactate. Therefore, we sought to understand if an association exists between these markers in early pregnancy and development of HDP in our population.Methods: This […]

Introduction and Objective: To investigate the associations between immune cell subset frequencies and metabolic features (including islet autoantibodies, fasting C-peptide [FCP], and HbA1c) in patients with type 1 diabetes (T1D) in China.Methods: This cross-sectional study enrolled 204 participants diagnosed with T1D. Flow cytometry was used to measure the immune cell subset (T/B/NK cells, Th cells, […]

Introduction and Objective: Despite the increased use of wearable technologies for self-management of type 1 diabetes, patients and families do not commonly download and review their data between clinic visits. The Diabetes, Data & Devices (D3) Education Program was developed to address this gap by providing structured education on diabetes data review and interpretation. This […]

Introduction and Objective: The benefits of diabetes self-management education and support (DSMES) are well-established. State Medicaid programs provide DSMES coverage. The objective was to obtain actionable data on utilization of DSMES among Medicaid enrollees with diabetes to inform strategies to increase use of services.Methods: This serial cross-sectional study analyzed Transformed Medicaid Statistical Information System (T-MSIS) […]

Introduction and Objective: Adolescents with type 1 diabetes (T1D) require contextually-aware, evidence-based self-management support. General-purpose large language models (LLMs) lack integration with systematically synthesized and appraised evidence or contextual tailoring. This study aimed to construct and evaluate T1DiaBot, a knowledge graph-grounded agent designed for adolescents with T1D.Methods: A self-developed “Evidence-to-Performance” (E2P) framework was followed: 1) […]

Introduction and Objective: Hypoglycemia causes an adrenergic response (AR) associated with epinephrine rise. We evaluated if change in heart rate (ΔHR), used as surrogate for AR, can distinguish between symptomatic and asymptomatic sensor-detected hypoglycemia (SDH), and factors affecting this, in type 2 diabetes. We focused on awake, symptomatic SDH<54mg/dL from people with intact awareness (Gold≤3), […]