Month: July 2025

Introduction and Objective: Digital health can improve outcomes for people with type 2 diabetes (T2D). Use of digital health tools, however, vary across patient populations. How health related social needs (HRSN) impact digital health use is largely unknown.Methods: Data from the 2022 Health Information National Trends Survey were analyzed to investigate the association between HRSN […]

Introduction and Objective: To amplify insulin secretion from beta cells with nutrient-stimulated hormone (NuSH) receptor agonists (e.g., the GLP-1 RA liraglutide (LIRA)), mitochondria must be energized via substrate-driven ADP privation. Since small-molecule modulators of Pyruvate Kinase (mPK) energize mitochondria via the phosphoenolpyruvate cycle and further boost LIRA-amplified insulin secretion, we hypothesized that mPKs could also […]

Introduction and Objective: Postoperative hypoxemia (PH) is the most common postoperative pulmonary complication (PPC) of bariatric surgery. However, clinically validated tools and tests are lacking to predict the risk of hypoxemia after bariatric surgery in patients with obesity. Therefore, this study developed and validated a nomogram model for predicting the probability of hypoxemia within 24 […]

Introduction and Objective: Pharmacotherapy offers a potential solution for individuals with overweight and obesity to decrease their body weight. However, there is limited knowledge of the effects of anti-obesity agents on the distribution of body fat.Methods: The PubMed, Embase, and Cochrane Library databases were reviewed for randomized controlled trials (RCTs) of weight-lowering drugs between inception […]

Introduction and Objective: ADA Standards of Care recommend screening for and addressing elevated DD, yet implementation is challenging. We built a validated, 8-item screener (T1-DDAS) into EPIC in the online e-CheckIn process for adults with T1D. A positive screen for DD (>= 2.0) generates a Best Practice Advisory (BPA) notification during the clinical encounter with […]

Introduction and Objective: Following the successful implementation of the Stuttgart Diabetic Ketoacidosis (DKA) Prevention Campaign at local level, we have extended this proven concept to the Federal State of Baden-Wuerttemberg (BW) in Germany.Methods: All public health departments (PHD) in BW were invited over 3 years to hand out flyers and posters about the typical symptoms […]

Introduction and Objective: Self-efficacy and diabetes distress are inextricably linked to coping with diabetes. The role of diabetes distress in the relationship between diabetes self-efficacy and glycemic control in T2DM over time is understudied. The objective of this study was to evaluate the longitudinal associations of self-efficacy with overall diabetes self-management, medication adherence, diabetes distress, […]

Introduction and Objective: Incretin drugs have demonstrated remarkable efficacy in body weight reduction and improving metabolic parameters. However, there may be challenges associated with lean mass loss and long-term health benefits. Urocortin-2 (UCN2) is a corticotropin-releasing factor receptor 2 (CRFR2) agonist and has been known to regulate whole body glucose metabolism, insulin sensitivity and skeletal […]

Introduction and Objective: Diabetes affects all cultures, yet inequities persist, especially among minority groups who often receive lower-quality care. Language barriers lead to inadequate blood sugar control and reduced engagement in Diabetes Self-Management Education (DSME). This report evaluates the effectiveness of a DSME team in integrating culturally competent translated care into primary care, enhancing services […]