Month: July 2025

Introduction and Objective: Metformin, the first-line treatment for type 2 diabetes, exerts antidiabetic effects partly through gut microbiota modulation. However, it can also increase Escherichia species capable of inducing endotoxemia via lipopolysaccharide (LPS). This study investigated metabolic endotoxemia, represented by LPS-binding protein (LBP) and its antagonist bactericidal/permeability-increasing protein (BPI), in relation to therapeutic responses to […]

Introduction and Objective: DSMES is considered a cornerstone of diabetes care. EAs with T1D are reported to have alarmingly low DSMES participation rates yet doing most of their self-care. In its present form, DSMES has been cited for not meeting EAs’ needs. Our objective was to discover factors affecting DSMES engagement and use a collaborative […]

Introduction and Objective: Induced adipocyte browning, in limited subcutaneous adipose tissue (SAT) human depots via cold activation or weight loss, confers anti-diabetic/obesity function via thermogenesis. Peroxisome proliferator-activated receptor-γ coactivator (PGC1-α) regulates mitochondrial biogenesis in adipose tissue (AT), and may activate telomerase reverse transcriptase (TERT), which regulates cellular aging. AT browning exists in GLP-1RA-treated patients with […]

Introduction and Objective: This pilot study sought to compare glucose outcomes and provider insulin dosing confidence in individuals using personal CGM while in the hospital compared to those receiving point of care blood glucose (POC BG) monitoring only.Methods: Hospitalized individuals followed by the diabetes service and expected to be discharged on insulin were included. Diabetes […]

Introduction and Objective: This study aims to evaluate the effectiveness of a digital lifestyle-based interventional program, developed by us, [D-LITE (Diabetes- Lifestyle Intervention for Therapeutic Enhancement)], on metabolic control in individuals with diabetes.Methods: An online diabetes management program utilizing a WhatsApp-based model facilitated continuous and collaborative care among patient, a dietitian, and physicians. The program […]

Introduction and Objective: Virtual diabetes management platforms can be used to improve glycemic control for people with diabetes. The objective of this study was to evaluate the effectiveness of the Diabetes Care Management coaching program in the Wellworks for You© (WW) chronic disease management virtual platform.Methods: A cohort of people with diabetes enrolled in the […]

Introduction and Objective: Body mass index (BMI), weight adjusted for height, is an imprecise tool for the diagnosis of obesity. Body composition assessment with bioelectric impedance analysis (BIA) scales estimate fat mass and % adiposity, offering a more precise diagnosis of obesity. The objective of this project was to compare the use of BMI and […]

Introduction and Objective: T1D management may require frequent interventions which disrupt the school day, though the missed class time and impact on students are not described. We aimed to determine the frequency, duration, and type of school disruptions for students with T1D.Methods: We analyzed data for 16 children (age 9.0±1.8 years, 62% female, 31% public […]

Introduction and Objective: This cost analysis compared FreeStyle Libre® systems (FSL) vs self-monitoring of blood glucose (SMBG) in T2D patients on basal insulin and poorly controlled (HbA1c > 8%), from a societal perspective in Spain.Methods: A model compared costs (€2024) of FSL and SMBG in a cohort of 1,000 T2D patients. The inputs, validated by […]

Introduction and Objective: Diabetes mellitus (DM) is a chronic condition characterized by elevated blood glucose levels due to insufficient insulin production or ineffective utilization. DM often coexists with thyroid diseases, particularly hypothyroidism, which can impact glycemic control and increase the risk of complications. Thyroid replacement therapy, typically with levothyroxine, is crucial for managing hypothyroidism in […]