Discussion This study represents the first and largest direct comparison of GLP-1 RAs and metformin in mitigating dementia risk among patients with T2DM. Historically, metformin has been the cornerstone of first-line therapy for T2DM due to its well-established efficacy in glycemic control and its potential neuroprotective effects.20–28 However, whether initiating GLP-1 RAs as first-line therapy […]
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Alkaline, Electrolyte, or Tap? Experts on the Best Water for Hydration
Share on PinterestDespite the popularity of trendy alkaline or electrolyte-infused waters, regular tap water can also help you stay sufficiently hydrated. Ekaterina Goncharova/Getty Images Proper hydration is essential for health, especially during the hot summer months. Alkaline or electrolyte-infused waters are often touted for their purported health benefits, but experts say tap water is cheaper […]
Read MoreCan the Viral Drink Actually Relieve Stress?
Share on PinterestTikTok users say the “cortisol cocktail” can help lower stress, but experts are skeptical about the benefits. Flashpop/Getty Images Proponents of the viral “cortisol cocktail” claim the drink can reduce stress and improve sleep, but there’s little evidence to support this claim. Its main ingredient, magnesium, may help support stress relief, but the […]
Read MoreUltra-Processed Foods Directly Linked to Chronic Diseases
Share on PinterestResearchers say there is strong evidence showing that ultra-processed foods promote overeating and increase the risk of obesity. Helene Cyr/Stocksy United A new report states that ultra-processed foods are a major contributing factor to the obesity epidemic. Researchers say these foods are designed to be palatable, causing people to overeat and gain weight. […]
Read MoreIntroduction and methodology: Standards of Care in Overweight and Obesity—2025
Collaborators: Collaborator group name: ADA Professional Practice Committee (PPC). Individual names (in order): Nuha A ElSayed, Vanita R Aroda, Louis J Aronne, Kirthikaa Balapattabi, Allison K Bennett, Sathyavathi Challa Siva Kanaka, Kathaleen Briggs Early, Angela Fitch, Stephanie L Fitzpatrick, W Timothy Garvey, Kimberly A Gudzune, Scott Kahan, Kamlesh Khunti, Robert F Kushner, Elizabeth J Pekas, […]
Read MoreWeight stigma and bias: standards of care in overweight and obesity—2025
Introduction People living with obesity face negative attitudes, stereotypes, and blame from others because of their weight (ie, weight bias).1 Weight bias can be explicit, such that an individual is conscious of negative attitudes (ie, blatant), or it can be implicit, where the person is unwilling or unable to admit these attitudes (ie, unconscious).2 Weight […]
Read MoreRisk of severe lower extremity arterial disease in elderly Japanese patients with type 2 diabetes: a propensity score-matched model analysis of sodium-glucose cotransporter 2 inhibitors versus metformin
Discussion Our study indicates that compared with metformin, SGLT2is may worsen severe LEAD in elderly patients with T2D, particularly those with low dBP. Revascularization is recommended in patients with LEAD based on their symptoms and Ankle-Brachial Index (ABI).19 A strong correlation between low dBP and abnormal ABI has been noted,20 21 with low dBP exacerbating […]
Read MoreCan Ozempic, Other GLP-1 Drugs Boost Low Testosterone?
Share on Pinterest A new study reports that GLP-1 medications may improve low testosterone in men with obesity or type 2 diabetes. Tatsiana Volkava/Getty Images New research shows that GLP-1 medications are associated with improved testosterone in males with obesity or type 2 diabetes. The findings align with prior evidence showing that weight loss can […]
Read MoreOlivia Munn Says Her Mom Has Breast Cancer After Taking Same Test
Share on Pinterest Olivia Munn shared that her mom, Kim Munn, was also diagnosed with breast cancer after taking the same risk assessment test. Getty Images Olivia Munn recently shared her mother was also diagnosed with breast cancer. The actress has been open about her breast cancer journey and revealed that her mom, Kim Munn, […]
Read MoreWHO Recommends Highly Effective, Twice-Yearly Shot for Prevention
Share on PinterestLenacapavir is a twice-yearly injection to prevent HIV that could improve adherence rates compared to other PrEP medications. d3sign/Getty Images The WHO issued a global recommendation for lenacapavir, a highly effective, twice-yearly injection to prevent HIV infection. The recommendation follows a recent FDA approval for the drug, which will be sold in the […]
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