Contributors: Concept and design: all authors (WT, BY, JP, JF, LEF-L, PCA, CJ, HR, DSL, AW, MEF, ASG, CLA, JCK, AH, VD, JU). Data analysis: BY, JP, JF, LEF-L, WT, PCA, JU. Interpretation of data: all authors (WT, BY, JP, JF, LEF-L, PCA, CJ, HR, DSL, AW, MEF, ASG, CLA, JCK, AH, VD, JU). Drafting: WT and JU. Critical revisions: all authors (WT, BY, JP, JF, LEF-L, PCA, CJ, HR, DSL, AW, MEF, ASG, CLA, JCK, AH, VD, JU). Approval of manuscript: all authors (WT, BY, JP, JF, LEF-L, PCA, CJ, HR, DSL, AW, MEF, ASG, CLA, JCK, AH, VD, JU). Guarantor: JU.
Funding: This work was funded by the Ted Rogers Centre for Heart Research Innovation Fund COVID-19 award and a Canadian Institute for Health Research Strategy for Patient-Oriented Research Innovative Clinical Trial grant (MYG-151211).
Competing interests: JU has received speaker/consulting honoraria from Amgen, Boehringer Ingelheim, Janssen, Merck, Novartis, Sanofi, and grant support to his institutions from AstraZeneca, Bayer, Boehringer Ingelheim, Janssen, Novartis, Sanofi. DSL is the Ted Rogers Chair in Heart Function Outcomes, University Health Network, University of Toronto. MEF is the Peter Munk Chair in Multinational Clinical Trials at Peter Munk Cardiac Centre, University Health Network, University of Toronto. VD has received research grants from AstraZeneca.
Patient and public involvement statement: Patients or the public were not involved in the design, conduct, reporting, or dissemination of our research.
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