Category: Diabetes

Introduction and Objective: This post hoc analysis assessed the efficacy and hypoglycemia outcomes with once-weekly insulin icodec (icodec) vs once-daily (OD) basal insulin comparators in insulin-naive (ONWARDS 1, 3, 5) and insulin-experienced (ONWARDS 2, 4) adults with T2D by baseline BMI.Methods: Treatment outcomes were analyzed, by trial, across baseline BMI subgroups (<25, ≥25-<30, ≥30-<35, ≥35 […]

Introduction and Objective: GluVue is a free application designed to enhance the efficiency of continuous glucose monitoring (CGM) data analysis for healthcare providers. Its primary goal is to improve clinical workflows and patient care in diabetes management.Methods: GluVue is designed to integrate seamlessly with electronic health records (EHR) and provide real-time analysis of continuous glucose […]

Introduction and Objective: Insulin is essential for managing T1D, yet many young adults face systemic barriers that limit access and consistent use. This study examined factors associated with using less insulin than prescribed and not filling insulin prescriptions over a 12-month period.Methods: A secondary analysis was conducted using data from the Resilient Empowered Active Living […]

Introduction and Objective: Individuals with type 1 diabetes (T1D) have a greater risk of complications and reduced life expectancy compared with those without diabetes. It is hypothesized that age at T1D diagnosis impacts clinical complications and mortality.Methods: A nationwide retrospective cohort study was conducted. Individuals ≥18 years of age with T1D with ≥1 entry in […]

Introduction and Objective: Besides injection site avoidance, there is no treatment for lipohypertrophy (LH), a common complication of insulin therapy associated with variable, impaired insulin absorption and suboptimal glycemic control. We investigated a tension offloading patch (embrace®, approved to reduce post-incisional scarring) in adults with T1DM and LH.Methods: Participants with T1DM ≥3 years, aged 18-65, […]

Introduction and Objective: Diabetic foot ulceration is a complication of diabetes which may lead to lower extremity amputation and disability with impaired quality of life. It disproportionately affects persons of minority ethnic backgrounds who also have poorer outcomes. This study aims to develop a culturally appropriate diabetic foot education tool for foot ulcer prevention and […]

Introduction and Objective: This post hoc analysis assessed efficacy and hypoglycemia outcomes with once-weekly insulin icodec (icodec) vs once-daily (OD) basal insulin comparators in insulin-naive (ONWARDS 1, 3, 5) and insulin-experienced (ONWARDS 2, 4) adults with T2D by diabetes duration at baseline.Methods: Treatment outcomes were analyzed, by trial, across baseline T2D duration subgroups (<5, 5-<10, […]

Introduction and Objective: The recent FDA-approved drug, Tirzepatide, a dual GIP and GLP-1 receptor agonist, showed superior efficacy in type-2 diabetes mellitus management and weight reduction. Awareness of the real-world incidence of adverse events(AEs) is crucial for a clinician to advise optimal treatment that ensures the best quality of life for the patient. While RCT-based […]

Introduction and Objective: This post hoc analysis investigated whether IcoSema, a once-weekly (OW) combination therapy of basal insulin icodec and the GLP-1 analog semaglutide currently in development, offers a postprandial glucose (PPG) control benefit vs other insulin-based regimens.Methods: COMBINE 1 and 3, two 52-week, phase 3a trials, investigated IcoSema vs OW basal insulin (icodec; COMBINE […]

Introduction and Objective: Integrating digital health and machine learning (ML) is reforming clinical care by offering a personalized, data-driven approach to optimize interventions. This study utilizes Dario’s digital health platform data to gain insights into blood glucose (BG) patterns influenced by clinical and engagement factors, for developing personalized interventions.Methods: Retrospective data analysis was performed on […]