Category: Diabetes

Introduction and Objective: The reduction of the insulin Fractional Clearance Rate (FCR) is an early marker of insulin resistance and/or beta-cell disfunction that may be observed before prediabetes arises. Here we aim to investigate whether such reduction is associated with easily measurable anthropometric characteristics, like body mass index (BMI), age and gender.Methods: We studied 204 […]

Introduction and Objective: Type 1 diabetes in adults is frequently misclassified as type 2, delaying appropriate insulin treatment and leading to worse outcomes. We developed a probability-based tool that combines pre-laboratory clinical characteristics and laboratory results to estimate the likelihood of type 1 vs. type 2 diabetes among adults with new-onset diabetes across four geographic […]

Introduction and Objective: There is a need for interventions that respond to cultural strengths and psychosocial burdens of underserved youth with diabetes and their families. Religion/spirituality is a resource that Latinx youth and their parents may use when other resources are unavailable. There is a gap in knowledge about the religious/spiritual experiences and needs of […]

Introduction and Objective: The MiniMed™ 780G (MM780G) system (Medtronic Diabetes) integrated with the Instinct™ sensor (Abbott Diabetes Care) was recently launched in the United States (U.S.). Designed for use with MiniMed systems, the Instinct™ sensor provides another option for MM780G automated insulin delivery (AID), in addition to the Simplera Sync™ and Guardian™ 4 sensors. The […]

Introduction and Objective: The Inflation Reduction Act (IRA), effective January 1, 2023, capped monthly insulin costs for Medicare Part D beneficiaries at $35. Payor restrictions have created barriers to patient access on an innovative Inhaled mealtime Insulin Afrezza driven primarily by high out of pocket costs and prior authorization barriers. This IRA policy shift influenced […]

Introduction and Objective: Bedside clinical methods to screen diabetic peripheral neuropathy (DPN) are not reproducible and detect DPN late. In a recent study of diabetes patients, DPN was detected in 14.4% using the 10 g monofilament (10gMF), increasing to 51.5% with DPN-Check, a point-of-care device measuring sural nerve conduction velocity and amplitude. We evaluated whether […]

Introduction and Objective: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) prescription increased rapidly in Medicare for type 2 diabetes (T2D), with limited evidence on medical expenditures. We estimated expenditure changes using a matched controlled design.Methods: Using 2015-2023 Medicare fee-for-service claims, we identified beneficiaries aged ≥67 years with prevalent T2D, continuous Part A, B, and D enrollment, […]

Introduction and Objective: Rural populations experience higher diabetes burden and barriers to care. RDMPs may mitigate geographic barriers; however, evidence comparing rural and urban populations remains limited. The objective of this study was to evaluate whether enrollment (ENR), engagement (ENG), and glycemic outcomes among rural participants in an RDMP were non-inferior to urban participants.Methods: We […]

Introduction and Objective: The health and psychosocial impacts of recurrent severe hypoglycemic events (SHEs) and impaired awareness of hypoglycemia (IAH) in adults with type 1 diabetes (T1D) who use continuous glucose monitors (CGM) and insulin pumps remain poorly understood. This study describes the health and psychosocial burden of adults with T1D using CGM and insulin […]

Introduction and Objective: Insulin pump-based Automated Insulin Delivery (AID) therapy has significantly improved glucose control and reduced hypoglycemic risk in patients with Type 1 Diabetes (T1D), but is currently only approved to use with U-100 insulin, which can be problematic in patients with severe insulin resistance, due to frequent cartridge volume exhaustion, infusion site saturation, […]