Introduction and Objective: We examined differences in diabetes technology use and their association with diabetic ketoacidosis (DKA) and hypoglycemia, diabetes distress by race/ethnicity in young people with T1D.Methods: Patients between the age of 14 and 25 (n=601) seen in a large U.S. endocrinology clinic were contacted to complete surveys online, including demographic information, the T1D […]
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1386-P: Machine Learning Predicts T2DM Incidence Using Basic Clinical and Laboratory Parameters
Introduction and Objective: Artificial Intelligence (AI) and Machine Learning (ML) have the potential to improve risk prediction by identifying complex patterns in clinical and laboratory data, surpassing traditional approaches. ML has already shown success in detecting metabolic diseases, including Type 2 Diabetes Mellitus (T2DM). However, the ability to accurately forecast T2DM incidence is even more […]
Read More1498-P: Iron, Iron Overload Genes, and Diabetes Risk in African Americans
Introduction and Objective: Ferritin is one of the most reliable markers of body iron stores. While most of the known gene mutations associated with hemochromatosis are observed less frequently in Blacks, mutations in the SL40A1 gene (rarely observed in European ancestry populations), characterized by low hemoglobin and high ferritin levels, is more common in Blacks. […]
Read More1789-P: Advanced Age in Spontaneously Hypertensive Rats Induces Prediabetes by Alterations in Pancreatic Islets
Introduction and Objective: In the last decades, the increase in life expectancy has led to a demographic transition into an older adult population. Chronic affections like type-2 diabetes and hypertension increase their incidence in adults. Combined with the aging process, the onset of diabetes or hypertension is exacerbated, however there are few evidences regarding their […]
Read More1445-P: Suboptimal Management of Multimorbidity among Those with Diabetes in India—Findings from a Large Population Study
Introduction and Objective: There is limited evidence about management of multimorbidity among those with diabetes in India.Methods: We conducted a large population representative cross-sectional survey in North and South India (both rural and urban) using multistage cluster random sampling among 12284 adults aged ≥ 30 years. Trained interviewers administered a questionnaire to collect data on […]
Read More1255-P: Association of Gestational Diabetes with Maternal Weight Change in the Two Years prior to Pregnancy
Introduction and Objective: Although achieving a healthy weight prior to pregnancy is recommended, data on the association between preconception weight changes and pregnancy outcomes are limited. We examined the relationship between preconception weight trajectories and risk of GDM in a large, diverse cohort.Methods: We conducted a retrospective cohort study of 257,017 pregnancies resulting in singleton, […]
Read More1444-P: Impact of Semaglutide Shortage in Canadian Adults and Response in a Community Endocrinology Setting (SCARCITY Study)
Introduction and Objective: Semaglutide once-weekly(SOW)/Ozempic is used for the management of T2DM and/or obesity (off-label) in Canada. There was a supply shortage of SOW during Oct 2023- Jan 2024. We aimed to explore the glycemic impact, management changes and sentiments related to the shortage.Methods: A phone survey of 159 consenting adults prescribed SOW for T2DM […]
Read More118-OR: Social Determinants of Physical Activity in Young Adults with and without Prediabetes or Type 2 Diabetes
Introduction and Objective: Prediabetes (PreD) and type 2 diabetes (T2D) are increasingly common in young adulthood, a period of declining physical activity (PA). We investigated associations between individual- and community-level social determinants of health (SDOH) and PA in young adults with and without PreD or T2D.Methods: We conducted a cross-sectional study using survey and Fitbit […]
Read More1353-P: Asymptomatic Individuals with β-Thalassemia Trait in Southern China Having Falsely Low Hemoglobin A1c Levels Are Readily Identified by Their Low MCV, Low MCH, and High RDW Values
Introduction and Objective: Testing HbA1c in undiagnosed asymptomatic thalassemia traits/carriers in prevalent regions can be problematic because HbA1c values may falsely be altered, potentially leading to inappropriate management.Methods: This cross-sectional study evaluated 397 individuals who underwent annual health screening and thalassemia genetic testing in a tertiary care hospital. Of this cohort, 85 iron-deficient and 16 […]
Read More681-P: Medication Adherence in the Glycemia Reduction Approaches in Diabetes—A Comparative Effectiveness (GRADE) Study
Introduction and Objective: We examined medication adherence as a predictor of glycemic outcomes and evaluated treatment group differences in the GRADE study.Methods: GRADE participants (T2DM <10 years, HbA1c = 6.8-8.5%, on metformin monotherapy) were randomly assigned to add insulin glargine, glimepiride, liraglutide, or sitagliptin. The Emotional Distress Substudy followed 1,739 participants who self-reported adherence to […]
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