Science means constantly learning. “You have to constantly question yourself, because our understanding of the world changes all the time. We may have thought something 20 years ago which isn’t true anymore,” Sylvaine You says. “But it’s also very exciting, because you’re constantly discovering. New proteins, new molecules, new pathways, new mechanisms—it’s such a dynamic […]
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NUAK1 Promotes Diabetic Kidney Disease by Accelerating Renal Tubular Senescence via the ROS/P53 Axis
Diabetic kidney disease (DKD) progression involves intricate interactions among senescence, oxidative stress, inflammation, and fibrosis. This study systematically investigates the regulatory role and molecular mechanisms of NUAK1 in DKD pathogenesis. Bioinformatics analysis of Gene Expression Omnibus data sets identified NUAK1 as a differentially expressed gene, validated in human kidney proximal tubule epithelial (HK-2) cells, high-fat […]
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Does Aluminum in Vaccines Cause Peanut Allergies? What Experts Think
Share on PinterestExperts say there is no credible scientific evidence that aluminum in vaccines causes peanut or other food allergies. heather diehl/Getty Images HHS Secretary Robert Kennedy Jr. says aluminum in vaccines may be a factor in a child developing a peanut allergy. Experts say Kennedy’s comments are not based on credible scientific evidence. Children […]
Read MoreSpecial Edition – CVOTs Part 2
In this special series on The Cardiovascular Outcome Trials our host, Dr. Neil Skolnik will discuss the history and importance of the Cardiovascular Outcome Trials for diabetes medications. In Part 1 we discussed an historical perspective with Dr. Steven Nissen. Today we discuss with Dr. Darren McGuire the incredible evolution of the CVOTs since that […]
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Exposure to Light While You Sleep Raises Risk
Share on PinterestSleeping in total darkness may help lower your risk of cardiovascular disease. d3sign/Getty Images A recent study reports that exposure to light during sleep is associated with a higher risk of cardiovascular disease. During sleep, ambient light contributes to brain stress that can cause arterial inflammation, which may lead to a heart attack […]
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Text messaging interventions are associated with reductions in HbA1c among patients with diabetes: a systematic review and meta-analysis
Methods This systematic review and meta-analysis was conducted in accordance with the 2020 Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines and registered in PROSPERO (International Prospective Register of Systematic Reviews) (CRD42023416462).5 Literature search We conducted a systematic search of PubMed, EMBASE and the Cochrane Central Register of Controlled Trials for relevant papers published […]
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Plant-Based Diet More Effective for Prevention
Share on PinterestMost Americans would try a plant-based diet to prevent diabetes, a recent poll shows. Image credit: Maria Korneeva/Getty Images New research says people are willing to make dietary changes to help with diabetes. However, they don’t always understand which type of diet is best for diabetes. Research indicates that a plant-based diet is […]
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Ultra-Processed Foods May Raise Risk In Women
Share on PinterestUltra-processed foods may contribute to the risk of early-onset colorectal cancer in women, study warns. A new study reports that there is an association between ultra-processed foods and the risk of developing polyps that could progress into colorectal cancer in women under the age of 50. Experts say these findings back up previous […]
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Low-Cost Prescription Drug Program to Lower Costs of GLP-1s
Share on PinterestThe TrumpRx prescription drug savings program is expected to be available by early 2026. Eli Lilly and Novo Nordisk have agreed to sell their weight-loss drugs, Wegovy and Zepbound, through the new TrumpRx program. The portal site is expected to launch in early 2026 and will provide consumers the ability to buy prescription […]
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Interpretable machine learning model for predicting recurrence in patients with diabetic foot ulcers
Discussion Although researches on the recurrent risk factors of DFU have become increasingly profound, there is currently no systematic model to integrate these risk factors and accurately predict recurrent probability.34 35 In this study, we developed and validated the first multidimensional prediction model for DFU recurrence, which integrates metabolic, hematological, inflammatory and clinical management factors […]
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