Share on PinterestA new experimental weight loss drug from Eli Lilly shows dramatic results that rival current GLP-1 drugs and bariatric surgery. Image Credit: Scott Olson/Getty Images Eli Lilly recently announced phase 3 trial results for a promising new weight loss drug retatrutide. The dramatic results from the TRIUMPH-1 trial represent the greatest weight loss […]
Read MoreBackground and hypothesis Chronic kidney disease (CKD) is a global health and economic burden, particularly among individuals with type 2 diabetes (T2D). According to Kidney Disease: Improving Global Outcomes guidelines, key CKD indicators include urine albumin-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR). Although independent genetic loci for these traits have been reported, their […]
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Share on PinterestWatermelon contains powerful nutrients that may offer protection against cardiovascular disease. Image Credit: J. Anthony/Stocksy Research shows that watermelon may help improve heart health and lower your risk of heart disease. It also shows that this fruit may aid in overall nutrient intake for both adults and children. Individuals who consume more watermelon […]
Read MoreIntroduction Renal involvement in type 2 diabetes (T2DM) can be due to diabetes (diabetic kidney disease, DKD) or other causes (non-DKD, NDKD) or both (mixed kidney disease). Available clinical and laboratory parameters have limitations in predicting a diagnosis (gold standard renal biopsy). Long non-coding RNAs (lncRNAs) evaluated in preclinical models but unexplored in biopsy-proven kidney […]
Read MoreIntroduction Seroconversion (SV) marks islet autoimmunity (IA) onset and preclinical type 1 diabetes (T1D), yet the contributions beyond T and B lymphocytes remain unclear. We evaluated DNA methylation (DNAm)-derived immune cell ratios between T1D cases and controls around SV. Research design and methods High-resolution immune cell-type deconvolution of peripheral blood DNAm from nested case-control samples […]
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When dairy farmer Brie Hyde began experiencing chronic fatigue and joint pain, doctors treated her for Lyme disease. After years of worsening symptoms, she was diagnosed with Lupus. As a child, Brie Hyde dreamed of being a veterinarian. “I’ve always been an outdoorsy person, very animal fascinated,” she told Healthline. While attending the University of […]
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Share on PinterestResearch shows that perimenopause may be the ideal time to adopt lifestyle changes to help lower cardiovascular risks. Image Credit: Aleksandar Nakic/Getty Images A recent study suggests that perimenopause offers a “window of opportunity” for females to reassess cardiovascular risk and prompt lifestyle changes. The findings show that perimenopausal females may be two […]
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Share on PinterestResearchers say current aerobic exercise recommendations may not be sufficient to reduce cardiovascular risk. MoMo Productions/Getty Images Researchers say adults may need to quadruple the current weekly exercise recommendations to achieve substantial heart health benefits. Those with lower levels of fitness may need as much as 600 minutes of weekly aerobic activity to […]
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Share on PinterestEating more plants and fewer processed foods can help with weight management during menopause. Viktoriya Skorikova/Getty Images A new study found that diets rich in plant foods and low in processed meats and salt may help with menopause weight gain. Plant foods have nutrients linked with better metabolic health and a healthy gut […]
Read MoreObjective Diabetic foot ulcer (DFU) is a life-threatening complication associated with high amputation and mortality rates. While numerous topical therapies exist, their comparative efficacy and safety remain unclear. We aimed to compare the efficacy and safety of topical therapies for DFUs to identify optimal treatment strategies. Research design and methods We searched PubMed, Embase, and […]
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