Category: Diabetes

Introduction and Objective: Although continuous glucose monitoring (CGM) is not indicated for inpatient use, the COVID-19 pandemic provided opportunities for hospital use beyond clinical trials. This analysis explored adult use from the Dexcom Hospital Registry, a database of real-world inpatient CGM use.Methods: This retrospective analysis included two US sites (ICU and non-ICU). Demographics, point-of-care (POC) […]

Introduction and Objective: The classification of maturity-onset diabetes of the young (MODY) pertains to monogenic forms of diabetes possessing an autosomal dominant mode of inheritance. The two most commonly seen subtypes are MODY2 and MODY3, caused by loss of function variants in the Glucokinase (GCK) and HNF1A genes, respectively. Our patient is an 18-year-old Caucasian […]

Introduction and Objective: We evaluated how early body roundness index (BRI), an anthropometric using waist circumference, affected rates of gestational diabetes (GDM) and hypertensive disorders of pregnancy (HDP).Methods: This is a secondary analysis of the Nulliparous Outcomes in Pregnancy: Monitoring Mothers to Be cohort, which followed nulliparous patients during pregnancy. First visit natural waist circumference […]

Introduction and Objective: Quinoline drugs were used to treat malaria from as early as 17th century. However, aside from their potent anti-malarial effects, hypoglycemia was associated with the use of quinine during the treatment for malaria, which was attributed to the drug directly evoking insulin secretion through KATP channel inhibition. In this study, we aim […]

Introduction and Objective: Understanding physicians’ perceptions of Patient Support Programs (PSPs) is critical for optimizing their impact on patient engagement, adherence, and outcomes in metabolic care. PSPs aim to enhance cardio-metabolic care through features like personalized dietary guidance, self-management tools, affordability, and accessibility. This mapping exercise evaluates physicians’ perspectives to refine PSP design and implementation, […]

Introduction and Objective: Type 1 diabetes mellitus (T1DM) is associated with increased risks of adverse pregnancy outcomes. While Continuous Glucose Monitoring Systems (CGMS) improve glycemic monitoring, self-monitoring of blood glucose (SMBG) remains the primary method for most pregnant women due to accessibility and cost barriers. This study aimed to evaluate the association between time-in-range (TIR) […]

Introduction and Objective: Type 2 diabetes (T2D) is a major public health challenge in the U.S., accounting for 90-95% of all diabetes cases. Individuals with A1C levels above 8% face increased risks of complications; however, diabetes self-management education (DSME) can effectively reduce A1C levels. Proactive DSME is essential for managing these patients. This retrospective analysis […]

Introduction and Objective: Adipocytes expand remarkably in size during positive energy balance, closely linked to metabolic health. However, the molecular mechanisms underlying adipocyte hypertrophy remain poorly understood. This study aims to identify transcriptional drivers of adipocyte hypertrophy in obesity.Methods: Bioinformatics analyses of ChIP-seq on adipocytes under varying nutrient availability identify super-enhancers and their associated transcriptional […]

Introduction and Objective: Research on using electronic platforms to adjust diets for type 2 diabetes (T2D) patients with CGM data is scarce. This study aimed to evaluate the effectiveness of personalized dietary advice based on CGM data delivered through a digital platform for newly diagnosed T2D patients, focusing on glycemic control and management adherence.Methods: A […]

Introduction and Objective: To evaluate whether higher engagement with a ​​digital diabetes self-management and education support (DSMES) program + continuous glucose monitoring (CGM) integrated solution is associated with better clinical outcomes through a secondary analysis of a randomized controlled trial.Methods: Participants with type 2 diabetes and HbA1c ≥ 8% not using mealtime bolus insulin (26-83 […]