In this special series on The Cardiovascular Outcome Trials our host, Dr. Neil Skolnik will discuss the history and importance of the Cardiovascular Outcome Trials for diabetes medications . In Part 1 we discuss an historical perspective with Dr. Steven Nissan and how this has lead to the CVOTs that change the way we practice […]
Read MoreCategory: Diabetes
Proteogenomic Insights Into Type 1 Diabetes: Refining Biomarkers and Therapeutic Targets
We are writing in response to the article by Lu et al. (1), which was recently published in Diabetes. In their research, the authors identify four circulating proteins (CTSH, IL27RA, SIRPG, and PGM1) that could act as potential risk factors for type 1 diabetes (T1D). Through Mendelian randomization, they propose that these proteins could serve as […]
Read MoreDiabetic Neuropathy Part I
In this special three-part series we will be doing a deep dive into diabetic peripheral neuropathy. In this first episode Dr. Rodica Pop-Busui joins our host, Dr. Neil Skolnik to discuss the epidemiology, pathophysiology, clinical manifestations, screening and diagnosis of diabetic peripheral neuropathy. In part 2 we will cover pharmacologic treatment and in part 3 […]
Read MoreThe Satiety Awakens: Metformin Restores Intestinal Lipid Sensing
Fundación AECCPRYGN234908LOPEMinisterio de Ciencia e InnovaciónPDC2022-133958-I00PID2021-128145NB-I00RED2018-102379-TRTI2018-099413-B-I00Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia10.13039/501100008425ED431C 2024/10H2020 European Research Council10.13039/100010663Synergy Grant-2019- WATCH-810331 Source link
Read MoreDiabetes Core Update – February 2022
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians […]
Read MoreSweating the Small Stuff: A Closer Look at the Endocrine Pancreas Throughout Stages of Type 1 Diabetes Progression
Breakthrough T1D & Helmsley Charitable Trust3-SRA-2024-1589-A-BDiabetes Research Institute Foundation10.13039/100001078FY26 AwardNational Institute of Diabetes and Digestive and Kidney Diseases10.13039/100000062R01DK138369JDRF10.13039/1000226901-INO-2024-1548-A-N Source link
Read MoreTime in Range for Pregnancy February 202
In this special episode on continuous glucose monitoring (CGM) and time in range Dr. Dr. Nicole Ehrhardt joins our host, Dr. Neil Skolnik to discuss potential benefits of CGM use and time in range prior to and during pregnancy for women who have diabetes. Presented by: Neil Skolnik, M.D., Professor of Family and […]
Read MoreToward Data-Driven MODY Panels: Strong Evidence for NEUROD1 and PDX1 , Limited Support for APPL1 and WFS1
Canadian Institutes of Health Research10.13039/501100000024AD6-200177Japan Society for the Promotion of Science10.13039/50110000169124K11694 Source link
Read MoreDiabetes Core Update – March 2022
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians […]
Read MoreDistributed Control of Muscle Glucose Uptake: A Tribute to the Late Dr. David H. Wasserman by Revisiting a 2004 Diabetes Classic by Fueger et al.
The control of muscle glucose uptake (MGU) is distributed across delivery, transport, and phosphorylation of glucose. These steps have been defined as control points of MGU in vivo due to the application of isotopic tracer techniques to transgenic mouse models. Using these techniques in a classic study published in Diabetes, Fueger et al. demonstrated that overexpression in […]
Read More