Author: sugaradmin

Introduction and Objective: Effective diabetes management often relies on the use of advanced technologies such as continuous glucose monitoring (CGM) systems and insulin pumps. However, barriers to accessing and utilizing these tools can significantly hinder individuals with type 1 diabetes (T1D). To explore these challenges, we conducted focus groups and structured interviews with a diverse […]

Introduction and Objective: Prior work by the Michigan Collaborative for Type 2 Diabetes (MCT2D) demonstrated increased adherence to non-insulin guideline-directed medical therapy (NI-GDMT) for type 2 diabetes (T2D) over the past 4 years but insulin use remains unclear. We examined insulin use in MCT2D practices over this period.Methods: We analyzed pharmacy claims from 82,207 adults […]

Introduction and Objective: To investigate the prevalence of overweight or obesity among persons with type 1 diabetes (T1D) globally.Methods: Multiple databases were searched for observational studies reporting the prevalence of overweight or obesity in persons with T1D from the inception to March 2024. The pooled prevalences of overweight or obesity were calculated according to the […]

Introduction and Objective: The Stelo Glucose Biosensor offers real-time glucose data and insights to individuals not on insulin, with or without diabetes. This study assessed early user experiences to evaluate the impact of real-time glucose monitoring on glycemic outcomes and behavior in users with no diabetes (ND), prediabetes (PreD), or Type 2 Diabetes (T2D) during […]

Introduction and Objective: People living with type 1 diabetes (pwT1D) are at risk for micro and macrovascular complications, mental health issues, as well as higher risk for additional autoimmune diseases (AD+). We aimed to understand the association between additional ADs and T1D related physical and mental burdens in Canadian adults.Methods: This was a cross-sectional study […]

Introduction and Objective: Glucagon influences glucose tolerance by increasing nutrient-induced insulin secretion. After gastric bypass (GB), prandial glucagon levels rise, independent of the nutrient composition, and remain elevated in the latter phase of the meal, when glycemia dips below fasting level. Here, we investigated the effect of hyperglucagonemia (100-150 pg/ml), created by ‘exogenous glucagon infusion’, […]

Introduction and Objective: Studies suggest weight gain in type 1 diabetes (T1D) may parallel that of adults without diabetes. The impact of this on cardiometabolic risk factors in T1D is less known.Methods: Veterans with T1D in the Veterans Health Administration from January 1, 2022 to December 31, 2023 had BMI calculated using averaged heights and […]

Introduction and Objective: Food insecurity (FI), a lack of consistent access to nutritionally adequate and safe food, affects more than 10% of Americans. FI is associated with adverse health outcomes including obesity and diabetes, but there is limited data about the impact of FI in pregnancy. Our objective was to determine the association between maternal […]

Introduction and Objective: While many individuals with Type 1 Diabetes (T1D) are typically exempt from fasting for health reasons. In this context, the Glycemia Risk Index (GRI) is a valuable tool for assessing glycemic quality. This study investigates the effects of Ramadan fasting on glycemic control in T1D, focusing on GRI and its components for […]

Introduction and Objective: The catalytic (NKAα1) and auxiliary (NKAβ1) subunits of the NKA protein complex are highly expressed in α-cells, yet their influence is poorly understood. Given the importance of NKA to cation handling and membrane potential regulation, we aimed to define the role of NKA in tuning α-cell Ca2+-handling and glucagon secretion.Methods: Electrophysiology, fluorescence […]