Share on PinterestAs the Jonas Brothers celebrate their 20th year as a band, it’s also been 20 years since Nick Jonas’ type 1 diabetes diagnosis. Photo courtesy of Dexcom Lead singer Nick Jonas has been living with type 1 diabetes for 20 years. The Jonas Brothers band “JONAS20: Greetings from Your Hometown Tour” celebrates its […]
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Portfolio Diet May Help Improve Heart Health, Lower Cholesterol
Share on PinterestAdherence to the Portfolio Diet may reduce the risk of death from heart disease by 18%. Image Credit: Ina Peters/Stocksy Research has linked adherence to the Portfolio Diet with a reduction in the risk of death from heart disease by up to 18%. The diet’s success comes from combining four specific cholesterol-lowering food […]
Read MoreWhat This Means for Medicare Recipients
Share on PinterestReclassification of cannabis will offer certain coverage for Medicare recipients. Image credit: Virginian Pilot/Getty Images A White House directive is ordering federal authorities to speed up the reclassification of a form of cannabis as a less dangerous drug. The action may also establish a pilot program that allows Medicare recipients to be reimbursed […]
Read MoreAre Wholegrains and Omega-3 the Key to Happiness? What Experts Say
Share on PinterestResearch shows that certain foods can affect your mood in different ways, including making you happier. Image Credit: Ani Dimi/Stocksy Research shows that certain foods can affect your mood in different ways. A recent study notes that a diet that is high in ultra-processed foods and refined carbohydrates can increase a person’s risk […]
Read MoreEating Nuts Linked to Fewer Cravings for Sweets, Study Finds
Share on PinterestYoung adults with a higher risk of metabolic syndrome may benefit from eating nuts, researchers say. fcafotodigital/Getty Images A new study suggests that swapping high carb snacks for nuts can help curb sweet cravings. Participants at risk for metabolic syndrome who made the switch also tended to increase their protein intake. Nuts are […]
Read MoreAmy Sedaris Shares How She Stays Mentally Sharp and Young at Heart
From multivitamins to crafting with friends, the ‘Strangers With Candy’ star shares her recipe for staying mentally sharp and young at heart. Share on PinterestActor and comedian Amy Sedaris shares her approach to healthy aging and cognitive well-being. Image credit: Axelle/Bauer-Griffin/Getty Images The macabre humor of Amy Sedaris may not be for the faint of […]
Read MoreParadoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels
Pancreatic β-cell ATP-sensitive K+ (KATP) channel closure underlies electrical excitability and insulin release, but loss or inhibition of KATP channels can lead to paradoxical crossover from hyperinsulinism plus hypoglycemia, to glucose intolerance or diabetes. We report genotype-phenotype information from a set of patients clinically diagnosed with maturity-onset diabetes of the young (MODY) and carrying coding […]
Read MoreDickkopf-3 (DKK3) and the Progression of Diabetic Kidney Disease in Primary Health Care
Accurate prediction of diabetic kidney disease progression is challenging, but mandatory. Urinary Dickkopf-3 (uDKK3), a tubular, epithelial-derived glycoprotein and marker of tubular injury, is a promising biomarker for kidney function decline. We explored the clinical utility of uDKK3 to predict kidney function decline and adverse cardiovascular events in patients with type 2 diabetes mellitus (T2DM) […]
Read MoreStrategic Reduction of Hybrid Insulin Peptide Formation Significantly Delays Diabetes Onset in NOD Mice
Type 1 diabetes (T1D) is characterized by autoimmune destruction of insulin-producing β-cells. Recent evidence has implicated hybrid insulin peptides (HIPs) as targets of autoreactive CD4 T cells in human T1D patients and as critical autoantigens recognized by diabetogenic T cells in nonobese diabetic (NOD) mice. HIPs form within pancreatic islets through cross-linking reactions between proinsulin […]
Read MoreMaternal Obesity Programs Glucose Intolerance in Pregnant Female Offspring
Maternal obesity is a known risk factor for metabolic dysfunction in offspring; however, its effect on metabolism during pregnancy in female offspring remains unclear. This study investigated how maternal obesity, induced by high-fat (HF) feeding in C57BL/6J mice, affects the metabolic adaptation to pregnancy in female offspring. Dams were fed an HF diet (60% fat) […]
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