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Serological markers of exocrine pancreatic function are differentially informative for distinguishing individuals progressing to type 1 diabetes

May 1, 2025 by sugaradmin

Discussion We used RF modeling to collectively assess seven T1D-implicated serological markers, in combination with AAbs, GRS2, and demographic information, for their utility in classifying study participants according to AAb/T1D status in a cross-sectional cohort. We observed higher GRS2 values, younger age, and reduced lipase levels associated with ≥2AAb+ versus AAb− classification. While speculative, these […]

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How a Stage 4 Diagnosis at 38 Saved This Man’s Life

May 1, 2025 by sugaradmin

Share on PinterestWilliam Lindley was diagnosed with stage 4 colon cancer at 38 years old. Image Provided by William Lindley Colorectal cancer is on the rise in people under 50 years old. One man shares his journey of being diagnosed at 38 and the importance of regular screenings. Colonoscopies can detect colorectal cancer early and […]

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Diabetes Core Update July 2024

May 1, 2025 by sugaradmin

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians […]

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Outcome evaluation and cost-effectiveness analysis for an integrated multidisciplinary diabetic limb salvage program: a combined observational and simulation study

May 1, 2025 by sugaradmin

Discussion This study examined the effectiveness of the DEFINITE Care program by comparing clinical outcomes and healthcare utilization over 1 year with a matched historical control cohort. Additionally, we assessed the program’s long-term cost-effectiveness in managing DFUs in a simulated cohort in Singapore over 20 years. This is the first comprehensive study from an Asian […]

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Regular Prostate Cancer Screenings Linked to 23% Lower Risk of Death

May 1, 2025 by sugaradmin

Share on PinterestA new study found that 1 in 6 males skipped all of their prostate cancer screening appointments, leading to a 45% higher risk of death from the disease. pcess609/Getty Images Men who avoided prostate cancer screening were significantly more likely to die from the disease, according to a large European trial. The reasons […]

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Diabetes Core Update Special Edition Oral Health and Diabetes

May 1, 2025 by sugaradmin

In this special episode on Oral Health our host, Dr. Neil Skolnik will discuss the bidirectional relationship between oral health and diabetes with Dr. Wenche Borgnakke.  This special episode is supported by an independent educational grant from Haleon. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson […]

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Mechanism of TGIF1 on glycolipid metabolism disorders in mice with type 2 diabetes

May 1, 2025 by sugaradmin

Introduction Diabetes is mainly composed of type 2 diabetes (T2D) (90%), pathologically characterized by insulin resistance and beta cell dysfunction, which leads to insulin release and abnormal blood glucose levels, triggering inflammation and endothelial dysfunction, and damaging the vasculature of the kidneys, eyes, heart, and nerves.1 2 Currently, oral hypoglycemic agents are the main treatment […]

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Common Household Plastics Linked to Cardiovascular Disease, Death

May 1, 2025 by sugaradmin

Share on PinterestNew research linked microplastics found in common household products to a higher risk of cardiovascular disease and death. Carlo Franco/Getty Images A new study says plastics found in common household products can increase the risk of cardiovascular disease in people ages 55 to 64. Previous research has indicated that phthalates used in plastic […]

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Diabetes Core Update August 2024

May 1, 2025 by sugaradmin

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians […]

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Association between use of sodium-glucose co-transporter-2 inhibitor and the risk of incident dementia: a population-based cohort study

May 1, 2025 by sugaradmin

Discussion In our large population-based retrospective cohort study of patients with type 2 diabetes, 40 years of age and older, we observed fewer events of incident dementia among SGLT-2i users compared with DPP-4i users; however, there was no statistical significant association between the risk of dementia and SGLT-2i use compared with DPP-4i use among people […]

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