Introduction Increasing evidence suggests that liver fibrosis is an independent risk factor for cardiovascular disease. However, the mechanisms underlying this increased risk are still unsettled. The aim of this study was to explore the relationship between myocardial glucose metabolism and the severity of liver fibrosis. Research design and methods We evaluated insulin-stimulated myocardial glucose metabolic […]
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PMOS (Formerly PCOS) May Quadruple Risk of Heart Attack, Stroke
Share on PinterestA new study found that females with PMOS (formerly PCOS) may have a higher risk of developing cardiovascular disease. Image Credit: andreswd/Getty Females with polyendocrine metabolic ovarian syndrome (PMOS) were about four times more likely to develop heart or artery disease than those without it, according to a new study. The elevated risk […]
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Hormone Tracking Helped Me Better Understand My Cycle
Share on PinterestRumer Willis is sharing how hormone tracking helped her better understand her cycle, and why she’s encouraging other women to better understand their reproductive health. Photo by Victoria Wall Harris Rumer Willis says hormone tracking helped her better understand her cycle. Experts say at-home hormone tests may help confirm ovulation and guide fertility […]
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AHA Highlights Benefits, Safety Limits for Heart Health
Share on PinterestThe American Heart Association (AHA) states that up to 5 cups of black coffee a day is safe for most people. Image Credit: Filmstax/Getty The American Heart Association (AHA) published a statement confirming how much caffeinated coffee is safe to drink each day. Adding flavorings like sugar, cream, and syrups to coffee can […]
Read MoreMorning Elevation in Insulin Enhances Afternoon Hepatic Glucose Disposal in Dogs by Increasing Both Insulin Signaling and Glucose Action
The second-meal phenomenon refers to the improved glycemic response to a subsequent identical meal. We previously showed that morning hyperinsulinemia is a key mediator, priming the liver for enhanced net hepatic glucose uptake (NHGU) and glycogen storage during an afternoon hyperinsulinemic-hyperglycemic clamp. Postprandial NHGU is regulated by three primary mechanisms: insulin action, initiated by hyperinsulinemia; […]
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FDA May Ease Restrictions Despite Concerns From Experts
Share on PinterestPhoto taken on Aug. 23, 2021 shows the U.S. Food and Drug Administration in Silver Spring, Maryland, the United States. (Photo by Ting Shen/Xinhua via Getty Images) An FDA advisory panel is expected to vote on whether to allow seven types of peptides to be sold as compounded medications. Proponents describe wellness peptides […]
Read MoreRBP4 Aggravates Diabetic Retinopathy by Inducing Microglial Activation and Endothelial Inflammation
Diabetic retinopathy (DR) is recognized as an inflammatory neurovascular complication, with neuronal deficits preceding vascular symptoms. This study identified elevated serum retinol-binding protein 4 (RBP4) as a risk factor for DR, because it induces retinal neuronal injuries and exacerbates vascular defects. Vitreous RBP4 levels were significantly elevated in patients with DR compared with those with […]
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Eating an Avocado a Day May Lower Your Risk
Share on PinterestResearch shows that eating an avocado a day may help reduce heart disease risk in people with obesity. Image Credit: Thai Liang Lim/Getty A recent study has found that eating an avocado a day may help lower the risk of heart disease in people with obesity. The researchers found that this was associated […]
Read Moreα/β-Hydrolase Domain Containing 5 Supports Glucose-Stimulated Lipolysis and Insulin Secretion in Pancreatic β-Cells
Adipose triglyceride (TG) lipase (ATGL) is the rate-limiting enzyme of TG catabolism at the surface of lipid droplets (LDs). In pancreatic β-cells, lipolysis by ATGL increases with glucose and produces metabolites that support glucose-stimulated insulin secretion (GSIS). Upregulation of lipolysis by glucose is blunted in human islets affected by type 2 diabetes. However, how glucose […]
Read MoreErratum. Unilateral Primary Aldosteronism Lacking KCNJ5 Somatic Mutations Is Associated With an Elevated Risk of New-Onset Diabetes. Diabetes 2025;74:850–859
In the article cited above, the first affiliation for author Chieh-Kai Chan was incomplete as published. The complete affiliation is Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu City, Taiwan. Source link
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