Author: sugaradmin

Introduction and Objective: Insulin is secreted into the portal vein in response to nutrient ingestion. However, a significant proportion is extracted as it traverses the liver prior to reaching the systemic circulation. The effect of glucagon on hepatic extraction is uncertain. This is particularly germane to situations where postprandial suppression of glucagon is impaired, theoretically […]

Introduction and Objective: Gestational diabetes (GDM) and hypertensive disorders of pregnancy often co-occur and are the leading causes of maternal morbidity. We aimed to examine whether the risks of GDM and new-onset postpartum diabetes (PPDM) increase across gestational blood pressure (BP) categories following the current guidelines with lower thresholds for hypertension (systolic/diastolic BP ≥130/80 mmHg) […]

Introduction and Objective: The reduction of the insulin Fractional Clearance Rate (FCR) is an early marker of insulin resistance and/or beta-cell disfunction that may be observed before prediabetes arises. Here we aim to investigate whether such reduction is associated with easily measurable anthropometric characteristics, like body mass index (BMI), age and gender.Methods: We studied 204 […]

Introduction and Objective: Type 1 diabetes in adults is frequently misclassified as type 2, delaying appropriate insulin treatment and leading to worse outcomes. We developed a probability-based tool that combines pre-laboratory clinical characteristics and laboratory results to estimate the likelihood of type 1 vs. type 2 diabetes among adults with new-onset diabetes across four geographic […]

Introduction and Objective: There is a need for interventions that respond to cultural strengths and psychosocial burdens of underserved youth with diabetes and their families. Religion/spirituality is a resource that Latinx youth and their parents may use when other resources are unavailable. There is a gap in knowledge about the religious/spiritual experiences and needs of […]

Introduction and Objective: The MiniMed™ 780G (MM780G) system (Medtronic Diabetes) integrated with the Instinct™ sensor (Abbott Diabetes Care) was recently launched in the United States (U.S.). Designed for use with MiniMed systems, the Instinct™ sensor provides another option for MM780G automated insulin delivery (AID), in addition to the Simplera Sync™ and Guardian™ 4 sensors. The […]

Introduction and Objective: The Inflation Reduction Act (IRA), effective January 1, 2023, capped monthly insulin costs for Medicare Part D beneficiaries at $35. Payor restrictions have created barriers to patient access on an innovative Inhaled mealtime Insulin Afrezza driven primarily by high out of pocket costs and prior authorization barriers. This IRA policy shift influenced […]

Introduction and Objective: Bedside clinical methods to screen diabetic peripheral neuropathy (DPN) are not reproducible and detect DPN late. In a recent study of diabetes patients, DPN was detected in 14.4% using the 10 g monofilament (10gMF), increasing to 51.5% with DPN-Check, a point-of-care device measuring sural nerve conduction velocity and amplitude. We evaluated whether […]