Author: sugaradmin

Introduction and Objective: Clinical trials of sodium-glucose transporter 2 inhibitors (SGLT2i) in youth with type 2 diabetes (T2D) showed significant improvement in HbA1c% and fasting plasma glucose, yet there is limited real-world data on their use. This study sought to assess real-world use and effectiveness of SGLT2i medications in management of T2D in a diverse […]

Introduction and Objective: Studies assessing diabetes mellitus (DM) risk after COVID-19 infection have typically examined narrow periods of the pandemic or did not incorporate advanced causal inference methods. This study assessed the association of COVID-19 infection with incident DM 1-year post-infection, stratified by viral variant periods, among adults aged 20-80y.Methods: We analyzed electronic health record […]

Introduction and Objective: This study examines the impact of Sodium-glucose cotransporter 2 inhibitors (SGLT2is) and metformin on severe Lower extremity arterial disease (LEAD) progression in elderly patients with type 2 diabetes (T2D). Using propensity score matching, a three-year analysis compares their distinct effects on risk using a real-world claims database.Methods: This retrospective cohort study analyzed […]

Introduction and Objective: Monogenic diabetes (MD) accounts for 0.4% of all cases of diabetes and 1-5% of youth-onset diabetes. Diagnosis allows for improved care with targeted therapy and identification of affected relatives. However, several barriers currently prevent patients from receiving diagnoses. We aimed to elucidate the proportion of individuals with undiagnosed MD within the Rare […]

Introduction and Objective: To gain feedback from users and assess engagement with the DiabetesWISER (DWer) community forum and DiabetesWise (DW) website – a neutral and unbiased platform for diabetes technology and exercise resources.Methods: User testing was conducted to understand needs and utilization patterns of people with diabetes and healthcare providers (HCPs) using these platforms.Results: During […]

Introduction and Objective: A pilot randomized controlled trial among inner-city African Americans with poorly controlled type 2 diabetes (HbA1c >=8%) tested the feasibility and preliminary efficacy of conditional and unconditional cash transfers.Methods: 100 participants were randomized to receive: 1) unconditional cash transfers (UCT) of $500 per month for 6 months and mailed diabetes education every […]

Introduction and Objective: Cytokine profiling is crucial in understanding immune responses and disease mechanisms, yet existing analytical tools often fall short in addressing the unique complexities of cytokine data. This study introduces CytoProfile, an R-based software tailored for comprehensive cytokine analysis. The objective was to evaluate its integration of advanced statistical and machine learning methods […]

Introduction and Objective: This study compared accuracy and glycemic control using Dexcom G6 and G7 real-time continuous glucose monitors (rtCGM) integrated into an insulin infusion computer calculator (IICC) workflow for critically ill adult inpatients.Methods: A retrospective analysis evaluated 13 ICU patients using Dexcom G6 and 35 using G7, integrated into an institution-developed IICC workflow using […]

Introduction and Objective: To evaluate effects of a family program on adolescents with type 1 diabetes and their parents.Methods: Parent-adolescent dyads (n=157) were randomly assigned to the intervention condition or a waitlisted control. The intervention included 6 weekly 30-minute sessions for dyads to meet with an interventionist to learn communication and problem-solving skills related to […]

Introduction and Objective: Continuous glucose monitors (CGMs) are recommended for individuals with diabetes using rapid- or short-acting insulin, but many eligible individuals do not use them. This study compared healthcare costs and utilization between CGM users and non-users.Methods: Claims data from the Mariner Commercial Claims Database (January 1, 2010-April 30, 2022) were analyzed. Adults (≥18 […]