Aim Genetic variants associated with gestational diabetes mellitus (GDM, n=14 SNPs) were recently classified into two groups: type 2 diabetes predominant effects (Class-T, three SNPs) and GDM-predominant effects (Class-G, eight SNPs; three SNPs unclassified). We aimed to compare the effects of GDM-associated variants on glucose levels (fasting glucose and 2-hour post-OGTT) measured during versus post […]
Read MoreMonth: December 2025
High-density lipoprotein cholesterol and kidney disease progression in patients with type 2 diabetes mellitus: the Fukushima Cohort Study
Introduction Dyslipidemia is a major risk factor for cardiovascular disease in type 2 diabetes mellitus (T2DM), but its association with kidney disease progression remains incompletely defined. Although low high-density lipoprotein cholesterol (HDL-C) has been linked to diabetic nephropathy, evidence regarding hard kidney outcomes is limited. We examined the associations between HDL-C and kidney events in […]
Read MoreTrends in cardiovascular disease prevalence among adults with type 1 diabetes in the USA: analysis of commercial claims data, 2017-2021
Introduction Cardiovascular disease (CVD) is a common complication and major cause of mortality in people with type 1 diabetes (T1D). This study quantifies the prevalence of CVD among commercially insured adults with T1D in the USA from 2017 to 2021, overall and among age-defined and sex-defined subgroups. Research design and methods We used Merative MarketScan […]
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WHO Recommends GLP-1 Drugs for Obesity: What to Know
Share on PinterestThe WHO recommended GLP-1s as a treatment for obesity alongside a healthy diet and regular exercise. Milles Team/Stocksy New guidelines from the World Health Organization (WHO) recommend using GLP-1 medications to help manage obesity. The agency said the weight-loss drugs should be used in conjunction with a healthy diet and regular exercise. Experts […]
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Experts Discuss the Benefits and Risks
Share on PinterestNew research suggests that stopping GLP-1 drugs before pregnancy is linked to complications like gestational diabetes and preeclampsia. Tatsiana Volkava/Getty Images A recent study suggests that stopping GLP-1s before pregnancy may be linked to higher rates of complications and excessive gestational weight gain. Experts caution that the findings don’t necessarily prove causation and […]
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