Introduction and Objective: Studies suggest weight gain in type 1 diabetes (T1D) may parallel that of adults without diabetes. The impact of this on cardiometabolic risk factors in T1D is less known.Methods: Veterans with T1D in the Veterans Health Administration from January 1, 2022 to December 31, 2023 had BMI calculated using averaged heights and weights from medical records and were categorized as normal (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2), and obese (≥30.0 kg/m2). Demographic data and risk factors including HbA1c, HDL-C, LDL-C, triglycerides (TG), systolic and diastolic blood pressure (SBP; DBP) and estimated glomerular filtration rate (eGFR) were also extracted. Age-stratified overweight or obesity prevalence rates were estimated using logistic regression, adjusting for race and gender, and mean values for risk factors compared by BMI category.Results: Overall, 72.1% of Veterans with T1D were either overweight or obese, and the adjusted prevalence rates were 68.2%, 77.0%, and 66.9% for age categories 21-39, 40-59 and 60-74, respectively. Despite having lower HbA1c values, overweight and obese persons had higher SBP, DBP, TG and LDL-C levels, and lower HDL-C and eGFR compared to normal weight persons (Table).Conclusion: The prevalence of overweight or obesity is high in Veterans with T1D and is associated with an adverse cardiovascular risk profile that does not appear explained by differences in glycemic control.
N. Arani: None. A.S. Syed: None. S. Macwan: None. J. Koska: Employee; Amgen Inc. D.R. Miller: None. J. Zhou: None. P. Reaven: Research Support; Dexcom, Inc.
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