Introduction and Objective: Comorbid non-insulin dependent diabetes mellitus (NIDDM) and stroke significantly contribute to mortality among older adults. This study examines age-adjusted mortality rates (AAMRs) and disparities by demographics, region, and age groups to identify trends throughout the period.Methods: Mortality data from CDC records for 55-85+ years were analyzed. AAMRs per 100,000 and annual percentage changes (APCs) with 95% confidence intervals (CIs) were calculated using Joinpoint Regression.Results: Between 1999 and 2022, 209,001 deaths among adults aged 55-85+ were attributed to comorbid NIDDM and stroke, with women accounting for 111,481 and men 97,520 deaths. Urban-rural disparities revealed distinct patterns, with a marked increase in metropolitan areas post-2014. Racial disparities were pronounced, particularly among people of Asian/Pacific Island, with a steep increase post-2018. Age-stratified analysis showed a significant increase in mortality rates for ages 55-64 and 85+ from 2015 onwards compared to 1999-2014. Regional trends highlighted the West as having the highest AAMR, while the Northeast exhibited the lowest.Conclusion: Increasing mortality from comorbid NIDDM and stroke underscores increasing disparities across gender, race, age groups, and region. Targeted interventions are needed to mitigate these inequities.
S.Z. Ali: None. A. Qadeer: None. S. Khan: None. M. Waqas: None. M. Khawar: None. M. Raza: None. H. Asif: None. M. Kakakhel: None. S. Zain: None. M.Z. Haider: None. M. Aamir: None. R. Alcaraz: None. S.B. Dugani: None. R.W. Kirchoff: None.
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