665-P: Association between Housing Insecurity and Hemoglobin A1c among Adults with Type 2 Diabetes—A Cross-Sectional Analysis of the All of Us Research Program



Introduction and Objective: Housing insecurity is an upstream social determinant of the health factors associated with poor health outcomes. Among adults with diabetes, there is little evidence of an association between housing insecurity and glycemic control. Therefore, a secondary data analysis was conducted to assess the association between housing insecurity and hemoglobin A1C (HbA1C) among 695 adults with type 2 diabetes (T2D) in the United States.Methods: Data was obtained from the “All of Us research program” and analyzed using R programming. A multiple linear regression model was used to assess the association between housing insecurity and HbA1C while adjusting for all covariates.Results: It was found that compared with participants with stable housing, adults with T2D who experienced housing insecurity had a clinically and statistically significant higher HbA1C (Adjusted β = 0.50, 95% CI: 0.07 to 0.93, p = 0.0239) (Figure 1). Additionally, non-Hispanic Blacks had higher HbA1C compared to their non-Hispanic White counterparts (Adjusted β= 0.33, 95% CI: 0.08 to 0.57, p = 0.009). Lastly, men had significantly higher HbA1C than women (Adjusted β=0.32, 95% CI: 0.12 to 0.52, p =0.002).Conclusion: There is a need to incorporate screening for housing instability into patient assessments and facilitate connections with appropriate resources and support services to improve health outcomes.

Disclosure

E.A. Adawudu: None. E. Ekpor: None.

Funding

The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.



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