Introduction and Objective: Diabetic foot ulcers (DFUs) are a common complication of diabetes, presenting in patients with T1D and T2D. We aimed to compare DFU characteristics and outcomes stratified by T1 vs T2DM.Methods: All patients with a DFU hospitalized in an Atlanta Hospital between 01/2019 – 12/2021 were included. T1D and T2D status were determined using manual chart review. Diabetes due to pancreatic insufficiency or pancreatitis were excluded. The primary outcome was a composite of either major or minor amputation or death.Results: Among 696 patients, 33 (5%) had T1D and 663 (95%) had T2D. Eight (24%) patients with T1D and 135 (20%) patients with T2D experienced the primary outcome (p=0.35). Patients with T1D were significantly younger and had a higher HbA1c than those with T2D. Moreover, patients with T1D seldom had PAD or ESRD at the time of DFU-related hospitalization or when they experienced limb loss or death.Conclusion: We observed no difference in the risk of experiencing amputation or death in patients with T1D and T2D. In our study sample, patients with T1D had higher HbA1c than those with T2D and experienced amputation or death approximately 10 years before those with T2D.
J.E. Tyrrell: None. M.C. Schechter: None. R.R. DSouza: None. H.H. Chang: None. M. Fayfman: Research Support; Abbott, Dexcom, Inc.
National Institute of Diabetes and Digestive and Kidney Disease (5R21MD017943-02)
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