Share on PinterestFibermaxxing emphasizes fiber intake during meals and snacks, which could aid weight loss and help lower the risk of chronic diseases. Knape/Getty Images ‘Fibermaxxing’ is TikTok’s latest nutrition trend emphasizing fiber intake during meals and snacks. Nutrition experts say fibermaxxing can provide numerous health benefits, including weight loss and a reduced risk of […]
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Share on Pinterest“Japanese walking” is a low impact exercise protocol that may help improve cardiometabolic health. Jacob Wackerhausen/Getty Images Interval walking training (IWT) is a form of walking exercise developed by Japanese researchers to improve cardiometabolic health. Also known as “Japanese walking,” IWT is an accessible form of interval training for people of all ages […]
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Share on PinterestNew research suggests vitamin D may help slow the biological aging process by preserving the length of telomeres. Mariya Borisova/Getty Images A new study suggests that vitamin D supplementation may help preserve the lengths of the protective caps at the ends of chromosomes known as telomeres. Researchers say maintaining the length of telomeres […]
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Share on PinterestMiley Cyrus is among several celebrities who’ve shared their experiences with ovarian cysts. Gilbert Flores/Variety via Getty Images Pop star Miley Cyrus recently revealed she endured an ovarian cyst rupture during a New Year’s Eve party she hosted. The singer-songwriter said the ordeal was excruciating and she needed emergency medical attention. Ovarian cysts […]
Read MoreSmall glycemic increments (≤0.5 mmol/L) can exert suppressive actions on endogenous glucose production (EGP); however, it is unclear if this is an insulin-dependent or -independent process. Here, we performed a low-rate glucose infusion in control participants without diabetes and in people with type 1 diabetes (T1D) to better understand this phenomenon. Glucose kinetics, hormones, and […]
Read MoreHigh-affinity islet autoantibodies predict type 1 diabetes in mice and humans and implicate germinal centers (GCs) in disease pathogenesis. T follicular helper (Tfh) cells are increased in individuals with type 1 diabetes and alterations in Tfh-like cells in the peripheral blood predicted individual responses to abatacept. Tfh cells support GC responses and depend on the […]
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Share on PinterestWomen who reported higher intakes of high quality carbohydrates and dietary fiber had up to a 37% greater chance of living longer, healthier lives. Yipengge/Getty Images A new study builds on evidence supporting the effects of complex carbohydrate consumption on long-term health and longevity. The findings show that women who reported higher intakes […]
Read MoreType 1 diabetes (T1D) is an autoimmune disease mediated by autoreactive T cells. Our studies indicate that CD4 T cells reactive to hybrid insulin peptides (HIPs) play a critical role in T-cell–mediated β-cell destruction. We have shown that HIPs form in human islets between fragments of the C-peptide and cleavage products of secretory granule proteins. […]
Read MoreRevascularization strategies failed to improve outcome in patients with diabetes with peripheral artery disease (PAD). Histone modifications are key modulators of gene expression and could play a role in angiogenic response. This study investigates the role of chromatin remodelling in modulating angiogenesis in diabetes. RNA sequencing (RNA-seq), and angiogenic assays (cell migration and tube formation) […]
Read MoreDiabetic peripheral neuropathy (DPN) is a common diabetes complication with no currently available curative treatments. Here, we demonstrated that the protein level of G-protein–coupled receptor 40 (GPR40) is significantly repressed in the sciatic nerves (SNs) of DPN patients, as well as in the peripheral nerves, including dorsal root ganglia (DRG) and SNs, of streptozotocin-induced type […]
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