Introduction and Objective: Diabetes and adipose research generate rich datasets whose accessibility and integration are often limited. To address this challenge, we created the Mammalian Adipose Tissue Knowledge Portal (MATKP; matkp.org), an open community portal for multi-species mammalian adipose biology. MATKP is accessible to diverse users and aggregates data for adipose tissues and cell types, […]
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928-P: AI-Based Fully Closed Loop (FCL) Achieves Improved Glycemia vs. Hybrid Closed Loop (HCL) in People with Type 1 Diabetes (T1D)
Introduction and Objective: HCL is the preferred insulin delivery method for people with T1D, however mealtime carbohydrate counting limits benefit. Use of AI to implement automated insulin delivery (AID) algorithms, able to avoid mealtime interactions, could alleviate burden and broaden use. We tested the latest UVA AID neural network-based system (AIDANET) in FCL in a […]
Read More535-P: Objectively and Subjectively Measured Physical Activity in Chinese Immigrants with Type 2 Diabetes in New York City
Introduction and Objective: There is a paucity of objectively measured physical activity (PA) data in underserved populations. We examined objectively measured and self-reported PA among Chinese immigrants with type 2 diabetes (T2D) in NYC.Methods: We analyzed baseline data from 60 participants. PA was measured by a wrist-worn ActiGraph GT9X accelerometer and the International Physical Activity […]
Read More927-P: Unlocking the Predictors of Improved Time in Range for Users of Automated Insulin Delivery Systems during Ramadan Fasting—Findings from the Hybrid-Ram Randomized Controlled Trial
Introduction and Objective: Automated insulin delivery (AID) systems adjust insulin delivery based on real-time glucose readings, offering potential advantages over open-loop insulin delivery (OLID). Ramadan fasting presents unique challenge for individuals with type 1 diabetes (T1D) due to significant fluctuations in glucose levels. This study aimed to identify the predictor factors associated with achieving better […]
Read More1429-P: Planetary Health Diet—Associations with Cardiovascular Disease and Type 2 Diabetes Risks, and Long-Term Weight Change in Women with a History of Gestational Diabetes
Introduction and Objective: The Planetary Health Diet (PHD), introduced in 2019 by the EAT-Lancet Commission, promotes chronic disease prevention and environmental sustainability. However, evidence on PHD adherence and its association with type 2 diabetes (T2D), cardiovascular disease (CVD), and weight gain is scarce, especially among women with a history of gestational diabetes mellitus (GDM).Methods: We […]
Read More926-P: Automated Insulin Delivery vs. Open-Loop Insulin Delivery during Ramadan in Patients with Type 1 Diabetes in Saudi Arabia—The Hybrid-Ram Randomized Controlled Trial
Introduction and Objective: Automated insulin delivery (AID) systems, adjusting insulin based on real-time glucose readings, may offer advantages over open-loop insulin delivery (OLID), especially during Ramadan fasting, which poses challenges for individuals with type 1 diabetes (T1D).Methods: This dual-center, open-label, randomized controlled trial compared AID systems (Medtronic MiniMed 780G [M780] and Tandem T-slim Control IQ […]
Read More1659-P: Oxytocin Is Robustly Expressed throughout the Small Intestine in Individuals with and without Type 2 Diabetes and Serum Neurophysin I Levels Are Reduced after Roux-en-y Gastric Bypass
Introduction and Objective: Oxytocin has been proposed to have anorexigenic effects and the gene is among the most upregulated in the small intestine after Roux-en-Y gastric bypass (RYGB) surgery. We evaluated oxytocin and oxytocin receptor gene expression along the intestinal tract in individuals with and without type 2 diabetes, and assessed circulating concentrations of the […]
Read More925-P: Real-World Outcomes of the Integration of Omnipod 5 Insulin Pump and Freestyle Libre 2 plus Continuous Glucose Monitoring in Adults with Type 1 Diabetes
Introduction and Objective: Hybrid closed-loop (HCL) therapy has revolutionized the care for people living with type 1 diabetes (pwT1D). The integration of different technology devices evolves rapidly providing individuals with more options and flexibility. We aimed to assess real-world outcomes of the new HCL system integrating the tubeless Omnipod 5 insulin pump with FreeStyle Libre […]
Read More1258-P: Fasting Triglycerides Are Unaffected by Weekday Variation in Obese Pregnancy But Steadily Increase over Gestation—Implications for Prevention of Macrosomia
Introduction and Objective: The role of maternal lipids, especially triglycerides (TG), in contributing to excess fetal fat accretion in pregnancies affected by obesity or diabetes is of increasing interest, given supportive data in obesity. Outside of pregnancy, fasting TG (FTG) are reported as higher on Mondays, after the weekend. No such data exists in pregnancy. […]
Read MoreHeart Attack Deaths Decline in U.S., but Other Heart Issues Are Increa
Share on PinterestHeart disease overall has decreased by 66% since 1970, but it remains the leading cause of death among Americans. Tashdique Mehtaj Ahmed/Getty Images Heart attacks have become more survivable in the past 50 years, and are no longer the leading cause of heart disease-related deaths, a new study reports. As heart attack deaths […]
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