Introduction and Objective: Gestational diabetes (GDM) increases T2D risk seven- to 10-fold and doubles the risk of cardiovascular disease; however, people with a history of GDM may be unaware of these elevated risks. Our objectives were to 1) assess risk perception for T2D development among reproductive-aged people with a history of GDM (n=95) versus a […]
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1665-P: Novel Spatiotemporal Analysis for Exploring Intestinal L-Cell Genesis and Differentiation
Introduction and Objective: GLP-1 is secreted from enteroendocrine L cells and exerts multifaceted effects as well as its insulinotropic action. Recently, GLP-1 receptor agonists have been widely applied and have attracted attention as a treatment that not only improves hyperglycemia, but also prevents cardiovascular events. However, it remains unclear when, where, and how L cells […]
Read More566-P: Engagement Moderates mHealth Outcomes in Latine Adults with Type 2 Diabetes
Introduction and Objective: One static and two adaptive, personalized type 2 diabetes (T2D) education and support mHealth interventions recently showed comparable effectiveness in reducing A1c among low-income Latine adults with T2D. However, as the delivery of adaptive components was contingent on engagement [i.e., participants’ completion of ecological momentary assessments (EMA)], those who responded to fewer […]
Read More90-OR: Effects of Glucagon-Like Peptide 1 (GLP-1) Agonist Therapy on Islet Function in Adults with Pancreatic-Insufficient Cystic Fibrosis ( PI-CF) and Abnormal Glucose Tolerance (AGT)—Preliminary Results
Introduction and Objective: Preserving β-cell function may delay or prevent progression to CF-related diabetes, a major comorbidity in people with PI-CF. This study aimed to evaluate whether weekly GLP-1 agonist therapy improves β- and α-cell function and post-prandial glucose tolerance in people with PI-CF and AGT. Methods: In this randomized, open-label, cross-over study, participants received […]
Read More565-P: From Knowledge to Practice—Evaluating Diabetes Training for U.S. Physical Therapy Residents
Introduction and Objective: Exercise is key in diabetes management, yet patients’ knowledge and absence of exercise specialists may be limiting factors. Physical therapists (PTs), as exercise specialists, should be part of diabetes care. Yet PTs knowledge of diabetes in the US and abroad is limited. The aim of this study was to 1) compare baseline […]
Read More691-P: Quality of Life and Diabetes Distress among Children and Youth with Type 1 Diabetes and Their Parents in Kampala, Uganda—Cross-Sectional Survey
Introduction and Objective: Type 1 diabetes (T1D) causes significant stress in affected individuals, which may be worse in those from resource-limited countries. We assessed diabetes distress and quality of life (QOL) among Ugandan children and young adults with T1D and their parents.Methods: Patients aged 4-26yr from two paediatric T1D clinics in Kampala participated. Diabetes distress […]
Read MorePolyphenols in Coffee May Protect Against Type 2 Diabetes
Share on PinterestA new study reports that polyphenols in coffee may offer protection against type 2 diabets. pocketlight/Getty Images Researchers say black coffee can help lower the risk of type 2 diabetes. The findings of a new study suggest that people who regularly drink caffeinated and decaffeinated coffee benefit from some of the beverage’s naturally […]
Read More89-OR: Modeling the Decline of Beta-Cell Function in Presymptomatic Stage 2 Type 1 Diabetes
Introduction and Objective: Presymptomatic Stage 2 type 1 diabetes (T1D) is characterized by ≥2 autoantibodies and dysglycemia due to a progressive decline of β-cell function, eventually leading to symptomatic Stage 3 T1D. We aim to develop a risk progression model with the potential to assess the effectiveness of therapeutic interventions to delay T1D onset.Methods: Twenty-three […]
Read More1887-LB: Association of Serum 25(OH)D Concentration with Risk of Lower Extremity Peripheral Artery Disease and Diabetic Foot Ulcer in Patients with Type 2 Diabetes—A Retrospective Study
Introduction and Objective: Type 2 Diabetes (T2D) can lead to ischemic conditions in lower limbs and the following risk of diabetic foot ulcer (DFU). Data linking vitamin D and lower extremity arterial plague (LEAP) and its adverse event, i.e. DFU, are limited.Methods: We enrolled 7479 hospitalized patients (2378 men and 3105 women aged 30 to […]
Read More899-P: Study on the Efficacy and Safety of Henagliflozin Combined with Continuous Subcutaneous Insulin Infusion in the Treatment of Type 2 Diabetes—A Multicenter, Randomized, Open-Label, Controlled Study
Introduction and Objective: The use of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in diabetes treatment is expanding. This study evaluated the efficacy and safety of henagliflozin combined with continuous subcutaneous insulin infusion (CSII) in type 2 diabetes (T2DM) based on continuous glucose monitoring system (CGM).Methods: In this multicenter, randomized, open-Label, controlled study, 210 patients who had […]
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