Introduction and Objective: To investigate the prevalence of overweight or obesity among persons with type 1 diabetes (T1D) globally.Methods: Multiple databases were searched for observational studies reporting the prevalence of overweight or obesity in persons with T1D from the inception to March 2024. The pooled prevalences of overweight or obesity were calculated according to the survey period with random effect models.Results: Among adults with T1D, the prevalence of obesity exhibited an increasing trend from 3.3% (95%CI, 2.2-5.0) during 1985-1990 to 22.2% (95%CI, 17.9-26.9) during 2015-2020. The prevalence of overweight in adults with T1D showed a consistent trend, reaching its highest at 31.9% (95%CI, 27.5-36.4) during 2015-2020. As for children and adolescents with T1D, the prevalence of obesity has been consistently increasing during 1990-2010, from 6.3% (95% CI, 4.0-9.7) to 12.2 % (95% CI, 7.2-18.3) and had a slight decline during 2010-2020, from 11.3% (95% CI, 9.7-12.9) to 9.3% (95% CI, 6.7-12.4). The rate of overweight in the younger fluctuated around 20% over the past two decades. As for sex, the prevalence of obesity has an overall increasing trend in both males and females with T1D, with a higher proportion in females. As for region, increasing prevalence of obesity or overweight was observed across four continents during 1980-2020, among which America showed the highest rate.Conclusion: The global prevalence of overweight or obesity has been increasing in persons with T1D from 1980 to 2020. Weight management may be one of unmet clinical needs for future T1D management.
Y. Guo: None. C. Lin: None. X. Cai: None. Z. Li: None. R. Jiao: None. W. Yang: None. L. Ji: None. H. Wu: None. F. Lyu: None. S. Bai: None.
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