Introduction and Objective: Physical activity (PA) is a well-known intervention resulting in weight loss, improved physical fitness and metabolic parameters, thereby contributing to reduced risk of conditions such as type 2 diabetes, cardiovascular disease, hypertension, and hyperlipidemia. Interventions promoting healthy lifestyle are more likely to succeed if they are culturally tailored. The goal of this study is to assess the impact of a 48 week tiered, supervised, and culturally tailored PA intervention in obese AA women.Methods: This is a pilot, single arm study in obese AA females at risk for diabetes. The 48 week tiered exercise intervention included both in-person and virtual exercise sessions occurring 3 times/week with independent sessions starting at week 24. Outcome measures were assessed at baseline, 24- and 48 weeks. The supervised intervention included cardiovascular, resistance, balance, and flexibility exercises.Results: A total of 60 sedentary, obese AA females were enrolled in the study (mean age 51, weight 219 lbs, BMI 37, 31% hypertensive, 18% dyslipidemic, and 34% pre-diabetic. A total of 32 and 28 participants completed 24- and 48 weeks of exercise, respectively. Compared to baseline, significant improvements were seen as follows: 1) weight, body mass index, waist and hip circumference, and blood pressure at week 48; 2) functional mobility (timed up & go, 6-minute walk distance tests, and length walked) in both weeks 24 and 48; 3) total body fat (including arms, legs, trunk, and waist), percentage of lean tissue, and Norfolk Quality of Life-Fatigue Survey scores in both weeks 24 and 48; 4) HemoglobinA1c at week 24. There were no changes in fasting blood glucose, insulin, triglycerides, and cholesterol.Conclusion: These results indicate that a culturally sensitive, supervised exercise intervention for obese AA women can lead to sustained weight loss, increased functional mobility, reduced levels of fatigue and improvements in body composition as well as metabolic parameters.
H. Parson: None. K.S. Thomas: None. D. Wolf: None. C.M. Casellini: Employee; Eli Lilly and Company. J. Patel: None. T. Sears: None. M. Karpov: None. E.S. Siraj: Consultant; Novo Nordisk. Research Support; Novo Nordisk. Consultant; Boehringer-Ingelheim. Research Support; Boehringer-Ingelheim.
Eastern Virginia Medical School
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