Discussion This study provides the necessary analyses and specific information to guide decisions on the required measurement duration when estimating CGM-derived metrics. In contrast to some previous studies,3 6 7 12 the calculations were performed on individual patient data. That individual calculations can lead to different conclusions and decisions for individual patients, for example, within […]
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Share on PinterestThe CDC reports that 97% of measles cases in the U.S. are in people who are unvaccinated or whose vaccination status is unknown. FG Trade/Getty Images The growing measles outbreak in the U.S. has reached 884 confirmed cases, surpassing the total number of cases in 2024. The CDC issued a measles advisory for […]
Read MoreIn this special edition of Diabetes Core Update, host Neil Skolnik, MD, explores the timely and critical topic of compounded medications in diabetes care. Dr. Skolnik is joined by John Hertig, PharmD, MS, CPPS, Associate Professor at the Butler University College of Pharmacy and Health Sciences, and Ed Hernandez, Executive Vice President and President of […]
Read MoreThe unfolded protein response (UPR) drives events that promote diabetic retinopathy, including vascular endothelial growth factor (VEGF) upregulation in Müller cells. How UPR is activated in vivo in the diabetic retina is not well understood. CD40 is required for development of diabetic retinopathy, but whether CD40 mediates activation of UPR sensors is unknown. CD40 ligation in […]
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As of 2023, an estimated 281 million people globally are international migrants—constituting approximately 3.6% of the world population, reflecting steady growth over the past years.1 Non-communicable diseases, including diabetes, disproportionately impact migrant and ethnic minority populations due to a combination of genetic, environmental and socioeconomic factors.2 Previous studies in the USA and Europe have shown that […]
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Share on PinterestHeavy menstrual bleeding is common during perimenopause and can lead to iron deficiency anemia, a well-known cause of fatigue. Maskot/Getty Images A recent study found that abnormal menstrual bleeding during perimenopause is associated with fatigue. If left untreated, heavy menstrual bleeding can lead to iron deficiency anemia, a well-known cause of fatigue. Females […]
Read MoreDiabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians […]
Read MoreDiabetic neuropathic pain is associated with elevated plasma levels of methylglyoxal (MGO). MGO is a metabolite of glycolysis that causes pain hypersensitivity in mice by stimulating the phosphorylation of eukaryotic initiation factor 2α (p-eIF2α) and subsequently activating the integrated stress response (ISR). We first established that Zucker diabetic fatty rats have enhanced MGO signaling, engage […]
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Discussion This cross-sectional study indicates that women aged 18–45 years diagnosed with type 2 diabetes in South London are exposed to several factors that increase their pregnancy risk profile. With only 1 in 10 women in this cohort prescribed contraception by their GP, the risk of an unplanned pregnancy was high, even allowing for the […]
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Share on PinterestPeople who rely on compounded GLP-1 drugs say they might not be able to afford brand-name versions, which are often not covered by insurance. Iuliia Burmistrova/Getty Images The FDA has ordered compounding pharmacies to stop making less expensive versions of popular weight loss medications like Ozempic and Zepbound. The order comes after federal […]
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