Category: Diabetes

Introduction and Objective: Postoperative hypoxemia (PH) is the most common postoperative pulmonary complication (PPC) of bariatric surgery. However, clinically validated tools and tests are lacking to predict the risk of hypoxemia after bariatric surgery in patients with obesity. Therefore, this study developed and validated a nomogram model for predicting the probability of hypoxemia within 24 […]

Introduction and Objective: Pharmacotherapy offers a potential solution for individuals with overweight and obesity to decrease their body weight. However, there is limited knowledge of the effects of anti-obesity agents on the distribution of body fat.Methods: The PubMed, Embase, and Cochrane Library databases were reviewed for randomized controlled trials (RCTs) of weight-lowering drugs between inception […]

Introduction and Objective: ADA Standards of Care recommend screening for and addressing elevated DD, yet implementation is challenging. We built a validated, 8-item screener (T1-DDAS) into EPIC in the online e-CheckIn process for adults with T1D. A positive screen for DD (>= 2.0) generates a Best Practice Advisory (BPA) notification during the clinical encounter with […]

Introduction and Objective: Following the successful implementation of the Stuttgart Diabetic Ketoacidosis (DKA) Prevention Campaign at local level, we have extended this proven concept to the Federal State of Baden-Wuerttemberg (BW) in Germany.Methods: All public health departments (PHD) in BW were invited over 3 years to hand out flyers and posters about the typical symptoms […]

Introduction and Objective: Self-efficacy and diabetes distress are inextricably linked to coping with diabetes. The role of diabetes distress in the relationship between diabetes self-efficacy and glycemic control in T2DM over time is understudied. The objective of this study was to evaluate the longitudinal associations of self-efficacy with overall diabetes self-management, medication adherence, diabetes distress, […]

Introduction and Objective: Incretin drugs have demonstrated remarkable efficacy in body weight reduction and improving metabolic parameters. However, there may be challenges associated with lean mass loss and long-term health benefits. Urocortin-2 (UCN2) is a corticotropin-releasing factor receptor 2 (CRFR2) agonist and has been known to regulate whole body glucose metabolism, insulin sensitivity and skeletal […]

Introduction and Objective: Diabetes affects all cultures, yet inequities persist, especially among minority groups who often receive lower-quality care. Language barriers lead to inadequate blood sugar control and reduced engagement in Diabetes Self-Management Education (DSME). This report evaluates the effectiveness of a DSME team in integrating culturally competent translated care into primary care, enhancing services […]

Introduction and Objective: Metformin, the first-line treatment for type 2 diabetes, exerts antidiabetic effects partly through gut microbiota modulation. However, it can also increase Escherichia species capable of inducing endotoxemia via lipopolysaccharide (LPS). This study investigated metabolic endotoxemia, represented by LPS-binding protein (LBP) and its antagonist bactericidal/permeability-increasing protein (BPI), in relation to therapeutic responses to […]

Introduction and Objective: DSMES is considered a cornerstone of diabetes care. EAs with T1D are reported to have alarmingly low DSMES participation rates yet doing most of their self-care. In its present form, DSMES has been cited for not meeting EAs’ needs. Our objective was to discover factors affecting DSMES engagement and use a collaborative […]

Introduction and Objective: Induced adipocyte browning, in limited subcutaneous adipose tissue (SAT) human depots via cold activation or weight loss, confers anti-diabetic/obesity function via thermogenesis. Peroxisome proliferator-activated receptor-γ coactivator (PGC1-α) regulates mitochondrial biogenesis in adipose tissue (AT), and may activate telomerase reverse transcriptase (TERT), which regulates cellular aging. AT browning exists in GLP-1RA-treated patients with […]