Discussion In this study, we used the extensive data available in the UKB and identified six classes of individuals of European ancestry with T2D based on their HbA1c trajectories over a mean follow-up of 8.1 years from diagnosis. The reference class (A; “low and stable”) represents a trajectory previously observed in other studies. This class […]
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Association between multifactorial control and excess risk of liver diseases in type 2 diabetes: a prospective cohort study
Study population The UK Biobank is a population-based prospective cohort study, consisting of more than 500,000 adults from England, Scotland, and Wales. Participants completed touchscreen questionnaires, verbal interviews, and physical measurements, as well as provided biological samples. The study design and other detailed information on the UK Biobank have been fully illustrated in previous studies.18 […]
Read MoreUltra-Processed Foods May Harm Male Fertility, Study Finds
Share on PinterestUltra-processed foods may contain endocrine disrupters that negatively impact male fertility. New Saetiew/Getty Images Ultra-processed foods can increase the risk of multiple chronic health conditions, such as heart disease and type 2 diabetes. A new study found that a diet heavy in ultra-processed foods can harm male reproductive health and reduce sperm quality. […]
Read MoreProstate Cancer Cases Rising After Years of Decline, Study Finds
Share on PinterestProstate cancer cases have risen steadily over the past decade, a new report found. Maskot/Getty Images Prostate cancer rates rose over the past decade, following years of decline. The increase is driven by advanced prostate cancer diagnoses, even in males as young as 55. Experts say it’s time to reevaluate recommendations for PSA […]
Read MoreTLR5 influences the development of type 1 diabetes
Discussion In the present study, we have demonstrated a significant difference in TLR5 expression in the islets of Langerhans between patients with newly onset T1D and healthy controls, and the TLR5 expression correlated inversely to islet-infiltrating CD3 T cells in the same patients, as well as in diabetic NOD mice. Additionally, we identified a TLR5-related […]
Read MoreGLP-1 Drugs Help Prevent Hospitalization, Early Death
Share on PinterestWeight loss drugs could help improve health outcomes in people with heart failure. The Good Brigade/Getty Images Researchers report that the weight loss drugs semaglutide and tirzepatide can reduce the risk of hospitalization and death by 40% in people with a common type of heart failure. Experts say this large cohort study strengthens […]
Read MoreDiabetes Core Update – September 2025
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians […]
Read MoreEating Meat May Help Protect Against Cancer-Related Deaths
Share on PinterestA new study suggests that eating meat could slightly lower cancer-related death risk. Davide Illini/Stocksy United A new study has found no increased death risk from eating plant or animal protein. The findings also suggest that animal protein may slightly lower cancer-related death risk. Nutrition experts say there’s no need to alter general […]
Read MoreThe impact of learning disabilities on control, management, and outcomes of type 2 diabetes mellitus in the UK: an observational cohort study using the Clinical Practice Research Datalink
Introduction Adults with learning disabilities in the UK have a substantially higher risk of developing type 2 diabetes mellitus (T2DM) than the general population. This study aimed to assess the impact of living with learning disabilities on T2DM control, therapeutic management, vascular outcomes, and mortality in UK primary care. Research design and methods We conducted […]
Read MoreCannabis May Help You Sleep Better, Researchers Say
Share on PinterestA new study found that daily cannabis use improved sleep in people with insomnia. Getty Images Cannabis products consumed on a daily basis resulted in better sleep for people with insomnia in a new study. Participants also reported improvements in anxiety and depression as well as pain levels. Cannabis continued to reduce insomnia […]
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