Introduction and Objective: Excessive diabetes device alerts can be burdensome for people with diabetes. Frequent autocorrection boluses inherent to the MiniMed™ 780G (MM780G) system are shown to reduce nighttime (SG) alarms/alerts.1 The present study assessed SG alarm/alert burden and glycemia in system users with and without optional SG alerts on.Methods: Deidentified CareLink™ data (01FEB2025 to 31JAN2026) of global MM780G system users aged ≥16yrs with ≥10days of SG data were analyzed. Glycemic metrics, SG alarms/alerts and delivered insulin of users who did not turn on optional (low and high) SG alerts (OFF) were compared with those of users who had them on (ON). The aforementioned were also assessed for a subset using recommended optimal settings (ROS, 100mg/dL glucose target + active insulin time of 2hrs, for >95% of time).Results: Overall OFF users (N=10,204) had significantly reduced 24-hr day, daytime and nighttime alarms/alerts (p<0.001, for all) and fewer manual boluses (p<0.001), versus overall ON users (N=257,957) (Figure). While overall OFF users had a mean TIR and GMI of 69.9% and 7.1%, respectively, those using ROS had a higher TIR (74.3%), a lower GMI (6.9%) and similar alarms/alerts (with a low TBR<70mg/dL [1.7%] and LBGI [0.6]).Conclusion: When MM780G optional SG alerts were off, ROS effectively managed glucose levels and allowed users an 80% reduction in alarm/alert burden.
T. Cordero: Employee; Current; Medtronic. M. Liu: Employee; Current; Medtronic. C. Rodriguez: Employee; Current; Medtronic. J.J. Shin: Employee; Current; Medtronic. R. Vigersky: Employee; Current; Medtronic. J. McVean: Employee; Current; Medtronic.
This study is funded by Medtronic MiniMed.
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