Introduction and Objective: Sugar-sweetened beverages (SSBs) consumption has emerged as a critical public health concern globally. However, comprehensive analysis of its long-term impact on diabetes mellitus and chronic kidney disease (CKD) mortality across different socio-demographic contexts remains limited.Methods: Using Global Burden of Disease Study 2021 data, we analyzed SSB-attributable diabetes and CKD mortality trends across 204 countries (1990-2021). Age-standardized mortality rates were stratified by age and socio-demographic index (SDI), with projections through 2051 using Bayesian age-period-cohort modeling.Results: Global SSB-attributable deaths increased from 27,286 (95% UI: 42,134-11,099) to 74,657 (95% UI: 115,575-33,724) between 1990-2021. CKD showed the steepest mortality rate increase (AAPC: 1.99%), followed by diabetes (AAPC: 0.85%). Young adults (25-29 years) showed the highest CKD increase (AAPC: 2.78%). Low-middle SDI regions experienced dramatic increase (AAPC: 2.57%), while high SDI regions showed decline (AAPC: -0.39%). By 2051, projections indicate substantial increases in CKD (165%) and diabetes (73%) mortality among young adults, with high and middle SDI regions showing 213% and 246% increases respectively.Conclusion: SSB-attributable diabetes and CKD mortality has increased substantially, particularly among younger populations. The projected increase through 2051, especially in CKD among young adults and regions with rapid socioeconomic development, demands urgent targeted interventions.
C. Liu: None. M. Lu: None. Z. Xin: None.
Beijing High-Level Public Health Technical Talent Development Project Grant (03-44)
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