Introduction and Objective: The association between sedentary behavior (SB) and glycemic profiles in individuals with type 1 diabetes (T1D) is unclear. This study aimed to examine this relationship cross-sectionally.Methods: Ninety-three Japanese adults with T1D participated in this study (75 women; age: 45.0 [36.0-55.0] years, HbA1c: 7.3 [6.8-8.1] %, median [25%-75% quartiles]). Physical activity (PA) was measured using a triaxial accelerometer and classified according to intensity: SB (≤1.5 metabolic equivalents [METs]), light-intensity PA (1.6-2.9 METs), and moderate-to-vigorous-intensity PA (≥3.0 METs).Results: Participants spent a median of 543.6 minutes per day in SB. Longer SB was associated with lower time in range (TIR). Longer periods of prolonged SB (≥30 min) were associated with higher mean 24-hour sensor glucose values (SG), time above range (TAR), HbA1c, and lower TIR (Figure). Furthermore, multiple regression analysis revealed that prolonged SB was the only PA type significantly associated with SG, TAR, TIR, and HbA1c (β = 0.546, 0.565, −0.567, and 0.468, respectively).Conclusion: These results suggest that increased time spent in prolonged SB may contribute to the deterioration of glycemic profiles in individuals with T1D. Therefore, these factors should be considered when managing T1D.
H. Honda: None. N. Hashimoto: None. M. Zenibayashi: None. T. Takeuchi: None. A. Yamamoto: None. Y. Hirota: Speaker’s Bureau; Novo Nordisk, Sanofi, Eli Lilly and Company, Terumo Corporation, Sumitomo Dainippon Pharma Co., Ltd. Research Support; Medtronic, Kyowa Kirin Co., Ltd, Abbott Japan Co., Ltd.
Japan Association for Diabetes Education and Care (2017)
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