Category: Diabetes

Effective treatment strategies for diabetes-related pain are limited because of its complex pathogenesis, particularly brain mechanisms underlying this disease. The acid-sensing ion channel 1a (ASIC1a) has emerged as a key player in the development and treatment of various types of pain. We investigated the role of ASIC1a in diabetes-related pain and its molecular mechanisms in […]

How immune tolerance to pancreatic islets is lost in type 1 diabetes (T1D) is a central question in the field. Clues come from the cancer field, where CD4 and CD8 T-cell responses are detected to posttranslationally spliced proteins that form hybrid neoepitopes (1,2). The discovery of hybrid insulin peptides (HIPs) in pancreatic islets offers a […]

Bonami and colleagues (1) demonstrate an obligatory role of BCL6-driven T follicular helper (Tfh) cells in the pathogenesis of type 1 diabetes (T1D). Their findings reveal that Bcl6 deficiency in T cells protects against diabetes, thus highlighting BCL6 as a promising therapeutic target to ameliorate T1D. Source link

Why did diabetes cases in South Korea surge in the 1990s and early 2000s? “We’re not sure. It probably aligned with rapid economic growth and drastic lifestyle changes,” Soo Heon Kwak says. “More automobiles, high-energy food intake, less exercise.” He was attending Seoul National University College of Medicine at the time, and when choosing a […]

Issues and Events Source link

National Health and Medical Research Council10.13039/501100000925App2025795 Source link

In this special episode on Obstructive Sleep Apnea our host, Dr. Neil Skolnik will discuss an overview of OSA. In Part 2 we will take a deep dive into diagnosis, Part 3 will discuss treatment options, and Part 4 will look at cases. This special episode is supported by an independent educational grant from Lilly. […]

In this special episode on Hypercortisolism in Diabetes our host, Dr. Neil Skolnik, will discuss new evidence showing the surprising prevalence of Hypercortisolism in people with uncontrolled Type 2 Diabetes.  This special episode is supported by an independent educational grant from Corcept. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel […]

In this episode of Practice Pearls: Overcoming Therapeutic Inertia Dr. Andrew Bzowyckyj discusses overcoming resistance to treatment intensification. This is part of the American Diabetes Association’s Overcoming Therapeutic Inertia initiative supported by Strategic Sponsors AstraZeneca and Sanofi, plus Supporting Sponsors Merck and Novo Nordisk. This episode is sponsored by the Overcoming Therapeutic Inertia  Initiative – […]

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians […]