Transplanted islet functional β-cell mass is measured by β-cell secretory capacity derived from the acute insulin response to glucose-potentiated arginine (AIRpot); however, data are limited beyond 1 year posttransplantation for individuals with type 1 diabetes. We evaluated changes in β-cell secretory capacity in a single-center longitudinal analysis and examined relationships with measures of islet cell […]
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Retraction: Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus
Alfaifi M, Ali Beg MM, Alshahrani MY, et al. Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus. BMJ Open Diab Res Care 2021;9:e001821. doi:10.1136/ bmjdrc-2020-001821 This article has been retracted by the journal due to peer review manipulation and concerns that the ethical approval supplied […]
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Why RFK Jr.’s Strategies Have Experts Worried
Share on PinterestHealth experts have raised concerns about HHS Health Secretary RFK Jr.’s strategies for containing measles outbreaks in Texas and other parts of the U.S. RONALDO SCHEMIDT/AFP via Getty Images HHS Secretary Robert F. Kennedy Jr. has recommended alternative treatment and prevention methods amid a growing measles outbreak in 22 U.S. jurisdictions Kennedy reversed […]
Read MoreDiabetes Core Update : Diabetes Core Update – Special Edition
In this special episode titled “Lipids – Beyond Statins and LDL Cholesterol”, our host, Dr. Neil Skolnik will discuss with two expert guests the details of treatment for LDL-Cholesterol, Triglycerides, and other lipid risk markers. This special episode is supported by an independent educational grant from Amarin. Presented by: Neil Skolnik, M.D., Professor of Family […]
Read More3D Imaging Resolves Human Pancreatic Duct–β-Cell Clusters During Cystic Change
Pancreatic cystic changes in adults are increasingly identified through advanced cross-sectional imaging. However, the impact of initial/intralobular epithelial remodeling on the local β-cell population remains unclear. In this study, we examined 10 human cadaveric donor pancreases (tail and body regions) via integration of stereomicroscopy, clinical hematoxylin and eosin histology, and three-dimensional (3D) immunohistochemistry, identifying 36 […]
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Association of glycemic control with Long COVID in patients with type 2 diabetes: findings from the National COVID Cohort Collaborative (N3C)
Collaborators: The N3C Consortium: Adam B. Wilcox, Adam M. Lee, Alexis Graves, Alfred (Jerrod) Anzalone, Amin Manna, Amit Saha, Amy Olex, Andrea Zhou, Andrew E. Williams, Andrew Southerland, Andrew T. Girvin, Anita Walden, Anjali A. Sharathkumar, Benjamin Amor, Benjamin Bates, Brian Hendricks, Brijesh Patel, Caleb Alexander, Carolyn Bramante, Cavin Ward-Caviness, Charisse Madlock-Brown, Christine Suver, Christopher […]
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Chronic Stress Linked to 78% Higher Stroke Risk In Young Women
Share on PinterestA new study found that moderate stress levels were associated with a 78% increased risk of stroke in female participants, but not in males. ozgurcankaya/Getty Images Stress is considered a modifiable risk factor for stroke. A new study found that stress may have a more significant impact on stroke risk in females than […]
Read MoreDiabetes Core Update Oct 2024
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians […]
Read MoreNew Model of Experimental Diabetic Cardiomyopathy Using Combination of Multiple Doses of Anomer-Equilibrated Streptozotocin and High-Fat Diet: Sex Matters
Diabetes leads to a more rapid development of diabetic cardiomyopathy (dbCM) and progression to heart failure in women than in men. Combination of high-fat diet (HFD) and freshly injected streptozotocin (STZ) has been widely used for diabetes induction; however, emerging data show that anomer-equilibrated STZ produces an early-onset and robust diabetes model. We designed a […]
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Early increase in carotid intima-media thickness in women with childhood-onset type 1 diabetes compared with healthy peers: the Norwegian Atherosclerosis and Childhood Diabetes study
Research design and methods The Norwegian Atherosclerosis and Childhood Diabetes (ACD) study is a prospective population-based cohort study with follow-ups every fifth year. The cohort consists of subjects with childhood-onset T1D and a healthy control group with similar age and sex distribution. All examinations were conducted at Oslo University Hospital, Ullevål. Written informed consent was […]
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