Introduction and Objective: Young adults with type 1 diabetes (T1D) have higher glycemia than other age groups, yet in this time of childbearing potential there are limited data on how the transition to adult care impacts gestational outcomes.Methods: Retrospective chart review at the Barbara Davis Center for Diabetes between 2014 and 2020 of women with type 1 diabetes who transitioned from the pediatric to adult clinic prior to versus at time of pregnancy. Data were obtained from electronic medical records, hospital records, and Colorado and Wyoming vital statistics departments. Outcomes between groups were compared using Student’s t-test and chi-square tests.Results: Demographic data for all eligible pregnancies (n=55) showed that transitioning prior to pregnancy was associated with older maternal age (p=0.041, Table). For included pregnancies (n=31), transitioning at pregnancy was associated with greater WIC utilization (p=0.041) and a higher rate of infant birthweights >4,500g (p=0.03). No other significant differences were seen, though there was a trend of larger infants in those transitioning at pregnancy (Table).Conclusion: Timing of adult transition was not associated with significant differences in most maternal or neonatal outcomes. Further study on the impact of maternal age is required as the young adult health outcomes appeared to be worse than those of older pregnant women with T1D.
L.A. Waterman: None. J.K. Snell-Bergeon: Stock/Shareholder; GlaxoSmithKline plc. S. Polsky: Research Support; Dexcom, Inc., Hemsley Charitable Trust, National Institute of Diabetes and Digestive and Kidney Diseases, Juvenile Diabetes Research Foundation (JDRF). Consultant; Medtronic.
NIH/NCRR Colorado CTSI (UL1 RR025780)
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