Introduction and Objective: Diabetes (DM) is an independent risk factor for ischemic heart disease (IHD). We aim to investigate disparities in diabetes-related ischemic heart disease (DRIHD) mortality trends within specific epidemiological groups.Methods: We extracted data from the CDC WONDER database from 1999 to 2020.IHD was listed as the main cause of death (ICD codes: I20-I25), while DM as a contributory cause (ICD codes: E10 -E14). We calculated the Age-Adjusted Mortality rate (AAMR) per 100,000 people and annual percentage change using Joinpoint regression.Results: About 1,094,046 Individuals with DM died of IHD from 1999-2020. The overall AAMR was 14.8. Males, non-Hispanic Blacks, individuals aged 75-84 years, and people who lived in Rural areas had significantly higher AAMR. AAMRs among census regions were comparable. The AAMR of the entire cohort declined from 20.2 to 13.6 over the study period (Average Annual Percentage Change (AAPC): -2.06; 95% CI: -2.34% to -1.90). Higher AAPCs were also observed in females and people living in urban areas.Conclusion: Although DM-related IHD mortality has declined over the past 2 decades, disparities persist among Males, non-Hispanic blacks, rural dwellers, and individuals aged 75-84 years. These findings underscore the need for longitudinal studies to explore the drivers of disparities and targeted public health interventions.
E. Okorigba: None. P.A. Kwaah: None. S.A. Mensah: None. E.A. Agyemang: None. A.K. Carboo: None. G. Appah: None. H. Rashid: None.
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