Month: July 2025

Introduction and Objective: Substance use (SU) and SU disorders (SUDs) adversely affect diabetes management and increase the risk of diagnosed diabetes (DM) complications. We estimated disparities in the prevalence of SU, SUDs, and SUD treatment among those with SUDs (SUDT) among US adults with DM by sociodemographic characteristics.Methods: We used 2021-2022 National Survey on Drug […]

Introduction and Objective: β cell dysfunction is the driving force of type 2 diabetes mellitus (T2DM) pathogenesis. SIRT7 is an NAD+-dependent lysine deacetylase with diverse functions in glucose metabolism. However, its role in islet remains uncharacterized. Here, we explored the functional role of SIRT7 in β cell physiology and pathophysiology.Methods: We generated Sirt7 β cell […]

Introduction and Objective: Reducing loneliness and lack of social and emotional support (LSES) among adults with diabetes (DM) can improve diabetes management and health outcomes. Considering the distinct pathophysiology and risk factor profile of each diabetes type, we explored the prevalence of loneliness and LSES among adults with type 1 or type 2 DM using […]

Introduction and Objective: Comprehensive telehealth improves control of refractory chronic diseases in integrated health systems, but has seldom been implemented in fee-for-service (FFS) systems. We examined the use of comprehensive telehealth for uncontrolled T2D and hypertension in a FFS environment.Methods: This randomized effectiveness-implementation trial compared two 12-month mobile monitoring-enabled telehealth interventions: 1) a self-management program; […]

Introduction and Objective: Autosomal dominant hypocalcemia type 1 (ADH1) is a hereditary disease caused by activating mutation of calcium – sensing receptor (CASR) gene, manifested as low parathyroid hormone (PTH) levels, hypocalcemia and hypercalciuria. Its clinical manifestations range from mild asymptomatic to severe hypocalcemia, which may be accompanied by epileptic seizures in severe cases. To […]

Introduction and Objective: The rising prevalence of obesity and metabolic disorders, such as type 2 diabetes, highlights the need for effective dietary strategies to improve health outcomes. The Mediterranean diet has been well studied and shown to reduce chronic disease risk through its beneficial effects on body composition and glucose metabolism. The Australian Guide to […]

Introduction and Objective: Youth with T1D and elevated HbA1c experience higher rates of short- and long-term complications. While individuals from some racial and ethnic groups are at greater risk of disparities in HbA1c due to systemic barriers and discrimination, less is known about the impact on family functioning amongst youth already experiencing elevated HbA1c. This […]

Introduction and Objective: Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by a set of metabolic abnormalities, such as pathological adipose tissue (WAT) accumulation, dyslipidemia and type 2 diabetes mellitus (T2D). Two major components linking pathological WAT function and MASLD to T2D are perturbed cellular redox homeostasis and the onset of chronic deregulation of inflammatory […]

Introduction and Objective: Women with a history of gestational diabetes mellitus (GDM) face a high risk of type 2 diabetes, making lifestyle change for prevention essential. Cost and accessibility are barriers to lifestyle change programs. This study evaluated the relationship between patient activation and engagement with diabetes prevention strategies in women with a history of […]

Introduction and Objective: Health literacy reflects the ability to make appropriate health decisions and affects health outcomes. It therefore is an important parameter in patient care. Health literacy in patients undergoing coronary angiography is unclear and is addressed in the present study.Methods: We enrolled 697 consecutive patients undergoing coronary angiography for the evaluation of established […]